Results 101 to 110 of about 3,588,226 (297)
Simulation of marker-assisted recurrent selection in autogamous species
Crop Breeding and Applied Biotechnology, 2002 This work used computer simulation to evaluate marker-assisted selection (MAS) in recurrent selection of autogamous species. Base populations were simulated by crossing each of five inbred lines with two others.
Eduardo Bearzoti, Roland Vencovsky
doaj
Marker-assisted introgression in backcross breeding programs [PDF]
, 1996 The efficiency of marker-assisted introgression in backcross populations derived from inbred lines was investigated by simulation. Background genotypes were simulated assuming that a genetic model of many genes of small effects in coupling phase explains
Visscher, PM +5 more
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Simulation of marker assisted selection in hybrid populations
Genetical Research, 1994 SummaryA computer model is developed that simulates Marker Assisted Selection (MAS) in a population produced by a cross between two inbred lines. Selection is based on an index that incorporates both phenotypic and molecular information. Molecular markers contributing to the index and their relative weights are determined by multiple regression of ...
A, Gimelfarb, R, Lande
openaire +2 more sources
Marker-assisted selection for cyclaneusma minus in pinus radiata
, 2002 Marker-assisted selection for cyclaneusma minus in pinus ...
Tamsyn Crowley (13097181) +3 more
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Electronic Journal of Plant Breeding, 2018 Bacterial blight (BB) of rice caused by the pathogen Xanthomonas oryzae pv. oryzae and the insect gall midge (GM) (Orseolia oryzae) are two major limitations of rice production.
Krishnakumar R and, N. Kumaravadivel
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Marker‐assisted selection in cattle
Animal Biotechnology, 1992 Abstract Direct observation of genetic differences using molecular techniques has prompted investigation into the nature and amount of genetic variation in cattle. Utilization of molecular data will include parentage analysis, individual identification, sexing of embryos and clones and detection of genetic defects.
openaire +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source