Results 101 to 110 of about 269,198 (309)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Improving stress coping ability: comparison between the CYP17 genotype Of Ovis Aries and Capra Hircus [PDF]
, 2010 The ability of animals to adapt to stress is not only an animal health and welfare concern, but also influences reproduction potential and robustness. An important pathway involved in the stress response is the hypothalamic-pituitary-adrenal axis (HPAA ...
Cloete, S.W.P. +3 more
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Marker assisted selection ‐ an overview
Animal Biotechnology, 1994 Abstract The main force driving gene mapping in domestic animals, is the potential for using gene maps as a means of identifying and mapping the genetic loci responsible for genetic variation in traits of economic importance. The ultimate objective is utilizing this information for marker‐assisted selection (MAS) using DNA level polymorphisms.
openaire +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Collaborative project between CIAT and Cirad rice improvement through the use of synthetic populations [PDF]
, 2010 The Cirad/CIAT rice collaborative project focuses on the development and enhancement of rice synthetic populations through recurrent selection (RS) with the goal to develop and diffuse improved material, populations or lines, for various rainfed ...
Audebert, Alain +6 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A method for genotyping elite breeding stocks of leaf chicory (Cichorium intybus L.) by assaying mapped microsatellite marker loci [PDF]
, 2015 BACKGROUND: Leaf chicory (Cichorium intybus subsp. intybus var. foliosum L.) is a diploid plant species (2n = 18) of the Asteraceae family. The term "chicory" specifies at least two types of cultivated plants: a leafy vegetable, which is highly ...
Barcaccia, Gianni +5 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Selection for cacao resistance to Moniliasis assisted by molecular markers [PDF]
, 2011 The basidiomycete Moniliophthora roreri, the causal agent of moniliasis, occurs in many cocoa producer countries in South and Central Americas, but not yet in Brazil.
Clément, Didier +4 more
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Cisgenesis, a new tool for traditional plant breeding, should be exempted from the regulation on genetically modified organisms in a step by step approach [PDF]
, 2008 Modern potato breeding requires over 100,000 seedlings per new variety. Main reasons are (1) the increasing number of traits that have to be combined in this tetraploid vegetatively propagated crop, and (2) an increasing number of traits (e.g ...
Jacobsen, E., Schouten, H.J.
core +2 more sources