Results 81 to 90 of about 2,742,571 (248)
Detection of Microbial 16S rRNA Gene in the Serum of Patients With Gastric Cancer
Frontiers in Oncology, 2019 Aberrance in the blood bacterial microbiome has been identified and validated in several non-infectious diseases, including cancer. The occurrence and progression of gastric cancer has been found to be associated with alterations in the microbiome ...
Zhaogang Dong +24 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
ВивліоѳикаAgainst the backdrop of the war in Ukraine the field of Eighteenth-Century Russian Studies is in something akin to crisis mode, which has produced deep and thought-provoking reflections on how or whether the field needs to be reconceptualized (or ...
Gary Marker
doaj +1 more source
Teaching Critically about the “Myth of War”
Critical Education, 2010 Essay review of Whitewashing War - Historical Myth, Corporate Textbooks, and Possibilities for Democratic Education by Christopher R. Leahey. Foreword by E. Wayne Ross. Teachers College Press, Columbia University, 2010. Paperback: $22.95 ISBN 0807750433,
Perry M. Marker
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
OpenMaTrEx: a free/open-source marker-driven example-based machine translation system [PDF]
, 2010 We describe OpenMaTrEx, a free/open-source example based machine translation (EBMT) system based on the marker hypothesis, comprising a marker-driven chunker, a collection of chunk aligners, and two engines: one based on a simple proof-of-concept ...
Forcada, Mikel +11 more
core +1 more source
The Value of Original Natural Stone in the Context of Architectural Heritage
Geosciences, 2016 Natural stone is required for maintenance and repair of historically, archaeologically and culturally important structures to prevent deterioration due to weathering and use.
Dolores Pereira, Brian Marker
doaj +1 more source