Results 91 to 100 of about 2,742,571 (248)
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Marker-based estimate of heritability for each trait.
, 2020 Marker-based estimate of heritability for each trait.
Yoshinori Taniguchi (494315) +9 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Letter penned by Marker Tours promoting the Lincoln Heritage Trail tour
, 2023 Letter penned by Marker Tours promoting the Lincoln Heritage Trail tour. Enclosed with the letter are a trifold brochure and tour reservation card.https://scholarsjunction.msstate.edu/fvw-ephemera/1301/thumbnail ...
Marker Tours
core
Variation in the Exon 3–4 Region of Ovine KRT85 and Its Effect on Wool Traits
Animalsα-keratins are structural proteins in the cortex of wool fibres and assemble in an organized fashion into keratin intermediate filaments. Variation in these keratin proteins affects the structure and characteristics of wool fibre, making keratin genes ...
Wenqiong Chai +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Promotional Brochure from Marker Tours
, 2023 This object is a Marker tours brochure. It is enclosed in an envelope with a promotional letter and several brochures, which include: Mr. Lincoln’s Washington, John Wilkes Booth Escape Route Tour, The National Road, Washington Underground, and ...
published by Marker Tours (American)
core
SoftwareMobile Software Engineering has emerged as a distinct subfield, raising questions about the transferability of its research findings to general software engineering. This paper addresses the challenge of evaluating the generalizability of mobile-specific
Robin Nunkesser
doaj +1 more source