Results 71 to 80 of about 42,912 (321)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Correlation between gene expression profiles in muscle and live weight in dzhalginsky merino sheep

open access: yesRevista Colombiana de Ciencias Pecuarias
Summary Background: marker assisted selection methods of sheep require the identification of genes that positively and negatively affect meat quality.
Vladimir Trukhachev   +9 more
doaj   +1 more source

Marker assisted backcross breeding of Bg 358 (Oryza sativa L.) for the anaerobic germination tolerant QTL AG1

open access: yesTropical Agricultural Research, 2016
Sustainability of transplanting systems for rice crop establishment in Sri Lanka is threatened due to climatic changes and heavy rains. Tolerance to anaerobic germination (AG) stress is a key trait that will ensure good crop establishment in direct ...
A. B. Sartaj   +2 more
doaj   +1 more source

The ovine HIAT1 gene: mRNA expression, InDel mutations, and growth trait associations

open access: yesFrontiers in Veterinary Science, 2023
BackgroundThe hippocampal abundant transcript 1 (HIAT1) gene, also known as major facilitator superfamily domain-containing 14A (MFSD14A), encodes for a transmembrane transporter protein and has been previously shown to be associated with milk production
Yunyun Luo   +7 more
doaj   +1 more source

Study of inheritance and identification of QTLs linked to Ceratocystis wilt resistance in cacao [PDF]

open access: yes, 2012
Ceratocystis wilt (CW) in cacao, caused by Ceratocystis cacaofunesta, is a drastic disease that results in plant death. The pathogen was recently identified in the major cacao-producing region of Brazil-Bahia.
Clément, Didier   +5 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Weak Allele of FASCIATED EAR 2 (FEA2) Increases Maize Kernel Row Number (KRN) and Yield in Elite Maize Hybrids

open access: yesAgronomy, 2020
Meristems are central to plant growth and development, yet evidence of directly manipulating this control to improve crop yield is scarce. Kernel row number (KRN) is an important agronomic trait that can directly affect maize (Zea mays L.) yield. However,
Khuat Huu Trung   +15 more
doaj   +1 more source

Proceedings of the COST SUSVAR/ECO-PB Workshop on organic plant breeding strategies and the use of molecular markers [PDF]

open access: yes, 2005
In many countries,national projects are in progress to investigate the sustainable low-input approach.In the present COST network,these projects are coordinated by means of exchange of materials,establishing common methods for assessment and statistical ...

core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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