Results 71 to 80 of about 4,756,439 (283)

Statistical analysis of the associations between phenolic monoterpenes and molecular markers, AFLPs and SAMPLs in the spice plant Oregano

Herba Polonica, 2016
Introduction: Molecular markers are the examples of the contribution of genome technology to medicinal plant breeding through marker-assisted selection (MAS) for pharmaceutical quality.
Azizi Ali, Ardalani Hamidreza, Honermeier Bernd   +2 more
doaj   +1 more source

Prolactin promoter gene as marker assisted selection (MAS) for the control of broodiness of Kampung chicken

Jurnal Ilmu Ternak dan Veteriner, 2014
Preliminary research about MAS (Marker Assisted Selection) was conducted to detect broodiness trait of Kampung chicken. MAS currently is very important in situations, where the accuracy of selection is low, such as, traits with low heritability, e.g. broodiness trait and egg production.
Tike Sartika, S.S Mansjoer, A Saefuddin, H Martojo   +3 more
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A novel 22-bp InDel within FGF7 gene is significantly associated with growth traits in goat

Animal Biotechnology
Fibroblast growth factor 7 (FGF7) is involved in lipid metabolism, which is considered as a candidate gene with close relation with muscle development by eGWAs and RNA-Seq analyses. To date, limited research has been conducted on the relationship between
Xian-feng Wu, Yuan Liu, Ying-gang Wang, Fu Zhang, Wen-yang Li   +4 more
doaj   +1 more source

Identification of a new molecular marker C2-25 linked to the Fusarium oxysporum f.sp. radicis-lycopersici resistance Frl gene in tomato

Czech Journal of Genetics and Plant Breeding, 2014
Fusarium oxysporum Schlecht. f.sp. radicis-lycopersici Jarvis & Schoemaker (FORL) is a saprophytic fungus, responsible for the fusarium crown and root rot disease in tomato (Solanum lycopersicum L.).
Mirosława STANIASZEK, Wojciech SZCZECHURA, Waldemar MARCZEWSKI   +2 more
doaj   +1 more source

Efficiency of Marker Assisted Selection(MAS) over The Phenotypic Selection for Economic Traits in Economic Animals

Journal of Animal Science and Technology, 2002
The efficiency of marker assisted selection(MAS) over conventional selection index based sorely on phenotypic records was studied by deterministic simulation model. Parameter combination of heritability and amount of genetic variation due to the markers included in the index was employed. For the index with own phenotypic information vs. the index with
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Marker-Assisted Selection (MAS): Untapped Potential for Enhancing Food and Nutrition Securities in Sub-Saharan Africa

, 2022
Global food security has raised concerns for the rapidly growing population and extreme weather due to climate change. Conventional plant breeding deployed the current greatly fecund crops, but there must be an increase in the genetic improvement to meet the anticipated future demand.
Abdullahi, W.M., Mu'az, S.A., Togola, A., Mohammed, G.S., Umar, M.L., Ongom, P.O., Echekwu, C., Boukar, O.   +7 more
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source