Results 111 to 120 of about 1,210,643 (302)

Genomic Selection in Wheat Breeding using Genotyping-by-Sequencing

open access: yesThe Plant Genome, 2012
Genomic selection (GS) uses genomewide molecular markers to predict breeding values and make selections of individuals or breeding lines prior to phenotyping. Here we show that genotyping-by-sequencing (GBS) can be used for de novo genotyping of breeding
Jesse Poland   +10 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Dynamic Predictions with Time-Dependent Covariates in Survival Analysis using Joint Modeling and Landmarking [PDF]

open access: yes, 2013
A key question in clinical practice is accurate prediction of patient prognosis. To this end, nowadays, physicians have at their disposal a variety of tests and biomarkers to aid them in optimizing medical care.
Andrinopoulou, Eleni-Rosalina   +5 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Estrogen alpha and beta subtype analysis in breast carcinomas - newer prognostic marker in the making?

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2021
H L Kishan Prasad
doaj   +1 more source

Tape-Shaped, Multiscale, and Continuous-Readable Fiducial Marker for Indoor Navigation and Localization Systems

open access: yesSensors
The present study proposes a fiducial marker for location systems that uses computer vision. The marker employs a set of tape-shaped markers that facilitate their positioning in the environment, allowing continuous reading to cover the entire perimeter ...
Benedito S. R. Neto   +3 more
doaj   +1 more source

When et la hiérarchie propositionnelle

open access: yesCorela, 2003
This paper sets out to show how the marker when works in a specific example. The marker is here studied within one single utterance. It turns out that the meaning taken on by when is completely different form the one it is liable to have in all its ...
Emmanuelle Roussel
doaj   +1 more source

Genome Halving by Block Interchange [PDF]

open access: yes, 2011
We address the problem of finding the minimal number of block interchanges (exchange of two intervals) required to transform a duplicated linear genome into a tandem duplicated linear genome.
Ouangraoua, Aïda   +2 more
core   +2 more sources

Tevatron Beam Position Monitor Upgrade

open access: yes, 2011
This paper describes the development of a digital-based Beam Position System which was designed, developed, and adapted for the Tevatron during Collider Run II.Comment: 20 ...
Annala, G.   +26 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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