Results 41 to 50 of about 1,210,643 (302)

Proximal placement of lateral thigh skin markers reduces soft tissue artefact during normal gait using the Conventional Gait Model [PDF]

, 2016
A primary source of measurement error in gait analysis is soft tissue artefact. Hip and knee angle measurements, used regularly to guide clinical decisions, are particularly affected due to pervasive soft tissue on the femur.
Baker, RJ, Cockcroft, J, Louw, Q
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Ki67 (MIB-1) as a Prognostic Marker for Clinical Decision Making Before Extended Pleurectomy Decortication in Malignant Pleural Mesothelioma

JTO Clinical and Research Reports, 2021
Introduction: The role of surgery for early stage malignant pleural mesothelioma (MPM) remains controversial. Current expert opinion is only to treat patients surgically as part of multimodality therapy.
Robert A. Belderbos, MD, Alexander P.W.M. Maat, MD, Sara J. Baart, PhD, Eva V.E Madsen, MD, PhD, Ad J.J.C. Bogers, MD, PhD, Robin Cornelissen, MD, PhD, Joachim G.J.V. Aerts, MD, PhD, Edris A.F. Mahtab, MD, PhD, Jan H. von der Thüsen, MD, PhD   +8 more
doaj   +1 more source

Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study [PDF]

, 2016
Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is currently hampered by the lack of accurate and early biomarkers for diagnosis of AKI and the
Groesdonk, Heiner, Herget-Rosenthal, Stefan, Husi, Holger, Klingele, Matthias, Metzger, Jochen, Mischak, Harald, Mullen, William, Stalmach, Angelique   +7 more
core   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

The Art of Ganga Singing: Cultural Tradition of the Dinaric Area

Muzikološki Zbornik, 2019
Ganga, currently the most popular traditional vocal genre of the Dinaric area (stretching across Croatia and Bosnia and Herzegovina), is one of the last examples of the archaic style of music making, entirely different from traditional styles and genres ...
Joško Ćaleta
doaj   +1 more source

Somatic markers and explicit knowledge are both involved in decision-making [PDF]

Neuropsychologia, 2009
In 1994, it was proposed that decision-making requires emotion-related signals, known as somatic markers. In contrast, some authors argued that conscious knowledge of contingencies is sufficient for advantageous decision-making. We aimed to investigate the respective roles of somatic markers and explicit knowledge in decision-making.
Guillaume, Sébastien, Jollant, Fabrice, Jaussent, Isabelle, Lawrence, Natalia, Malafosse, Alain, Courtet, Philippe   +5 more
openaire   +3 more sources

Development of Optical Biosensor Technologies for Cardiac Troponin Recognition [PDF]

, 2015
Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events ...
Abdolrahim, Mojgan, Alhosseini, Sanaz Naghavi, Rabiee, Mohammad, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +5 more
core   +1 more source

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. [PDF]

, 2014
Spores of some species of the strictly anaerobic bacteria Clostridium naturally target and partially lyse the hypoxic cores of tumors, which tend to be refractory to conventional therapies. The anti-tumor effect can be augmented by engineering strains to
Dubois, L, Ehsaan, M, Heap, JT, Knox, R, Kubiak, AM, Kuehne, SA, Lambin, P, Mellaert, LV, Minton, NP, Paesmans, K, Theys, J   +10 more
core   +4 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source