Results 1 to 10 of about 2,729,076 (335)

A decade of research into classical swine fever marker vaccine CP7_E2alf (Suvaxyn® CSF Marker): a review of vaccine properties [PDF]

Veterinary Research, 2017
Due to its impact on animal health and pig industry, classical swine fever (CSF) is still one of the most important viral diseases of pigs. To control the disease, safe and highly efficacious live attenuated vaccines exist for decades.
Sandra Blome, Kerstin Wernike, Ilona Reimann, Patricia König, Claudia Moß, Martin Beer   +5 more
doaj   +7 more sources

A Novel E2 Glycoprotein Subunit Marker Vaccine Produced in Plant Is Able to Prevent Classical Swine Fever Virus Vertical Transmission after Double Vaccination [PDF]

Vaccines, 2021
The efficacy of a novel subunit vaccine candidate, based in the CSFV E2 glycoprotein produced in plants to prevent classical swine fever virus (CSFV) vertical transmission, was evaluated. A Nicotiana benthamiana tissue culture system was used to obtain a
Youngmin Park, Yeonsu Oh, Miaomiao Wang, Llilianne Ganges, José Alejandro Bohórquez, Soohong Park, Sungmin Gu, Jungae Park, Sangmin Lee, Jongkook Kim, Eun-Ju Sohn   +10 more
doaj   +3 more sources

Bungowannah Pestivirus Chimeras as Novel Double Marker Vaccine Strategy against Bovine Viral Diarrhea Virus [PDF]

Vaccines, 2022
Marker or DIVA (differentiation of infected from vaccinated animals) vaccines are beneficial tools for the eradication of animal diseases in regions with a high prevalence of the designated disease. Bovine viral diarrhea virus (BVDV)-1 (syn. Pestivirus A)
Susanne Koethe, Patricia König, Kerstin Wernike, Jana Schulz, Ilona Reimann, Martin Beer   +5 more
doaj   +3 more sources

Genetically distinct pestiviruses pave the way to improved classical swine fever marker vaccine candidates based on the chimeric pestivirus concept [PDF]

Emerging Microbes and Infections, 2020
Classical swine fever (CSF) is one of the most important viral diseases of pigs. In many countries, the use of vaccines is restricted due to limitations of subunit vaccines with regard to efficacy and onset of protection as well as failure of live ...
Alexander Postel, Paul Becher
doaj   +3 more sources

Evaluation of Safety and Efficacy of an Inactivated Marker Vaccine against Bovine alphaherpesvirus 1 (BoHV-1) in Water Buffalo (Bubalus bubalis) [PDF]

Vaccines, 2021
Recent studies have explored the seropositivity of Bovine alphaherpesvirus 1 (BoHV-1) in water buffaloes, suggesting the urgency for developing strategies to eradicate the virus involving both cattle and water buffaloes.
Stefano Petrini, Alessandra Martucciello, Francesco Grandoni, Giovanna De Matteis, Giovanna Cappelli, Monica Giammarioli, Eleonora Scoccia, Carlo Grassi, Cecilia Righi, Giovanna Fusco, Giorgio Galiero, Michela Pela, Gian Mario De Mia, Esterina De Carlo   +13 more
doaj   +3 more sources

A Synthetic Modified Live Chimeric Marker Vaccine against BVDV-1 and BVDV-2 [PDF]

Vaccines, 2020
Bovine viral diarrhea virus (BVDV), a pestivirus which exists in the two distinct species BVDV-1 (syn. Pestivirus A) and BVDV-2 (syn. Pestivirus B), is the causative agent of one of the most widespread and economically important virus infections in ...
Susanne Koethe, Patricia König, Kerstin Wernike, Florian Pfaff, Jana Schulz, Ilona Reimann, Birgit Makoschey, Martin Beer   +7 more
doaj   +3 more sources

Assessment of the Safety Profile of Chimeric Marker Vaccine against Classical Swine Fever: Reversion to Virulence Study [PDF]

Viruses
Chimeric marker vaccine candidates, vGPE−/PAPeV Erns and vGPE−/PhoPeV Erns, have been generated and their efficacy and capability to differentiate infected from vaccinated animals were confirmed in previous studies. The safety profile of the two chimeric
Loc Tan Huynh, Mikihiro Otsuka, Maya Kobayashi, Hung Dinh Ngo, Lim Yik Hew, Takahiro Hiono, Norikazu Isoda, Yoshihiro Sakoda   +7 more
doaj   +3 more sources

Early protection events in swine immunized with an experimental live attenuated classical swine fever marker vaccine, FlagT4G. [PDF]

PLoS One, 2017
Prophylactic vaccination using live attenuated classical swine fever (CSF) vaccines has been a very effective method to control the disease in endemic regions and during outbreaks in previously disease-free areas.
Holinka LG, O'Donnell V, Risatti GR, Azzinaro P, Arzt J, Stenfeldt C, Velazquez-Salinas L, Carlson J, Gladue DP, Borca MV.   +9 more
europepmc   +2 more sources

An Open-Label, Randomized Field Trial Demonstrates Safety and Immunogenicity of Inactivated gE-Deleted Marker Vaccine Against Infectious Bovine Rhinotracheitis in Cattle [PDF]

Vaccines
Background: Infectious Bovine Rhinotracheitis (IBR), Infectious Pustular Balanoposthitis (IPB), Infectious Pustular Vulvovaginitis (IPV), late-term abortions, and neurological and systemic disease are common manifestations of Bovine Herpesvirus-1 (BoHV-1)
Bhaskar Ganguly, Sarvesh Tayshete, Deepa Padinjare Melepat, Sudhakar Awandkar, Srinivas Karnati, Priyabrata Pattnaik, Anand Kumar Kanakasapapathy   +6 more
doaj   +2 more sources

A multi-factorial genetic model for prognostic assessment of high risk melanoma patients receiving adjuvant interferon [PDF]

, 2012
Purpose: IFNa was the first cytokine to demonstrate anti-tumor activity in advanced melanoma. Despite the ability of high-dose IFNa reducing relapse and mortality by up to 33%, large majority of patients experience side effects and toxicity which ...
Alessandro Monaco, Ena Wang, Francesco M. Marincola, Helen Gogas, John M. Kirkwood, Lorenzo Uccellini, Maria Spyropoulou-Vlachou, Monica C. Panelli, Sophia N. Karagiannis, Yingdong Zhao   +9 more
core   +35 more sources