Results 51 to 60 of about 2,729,076 (335)

TIV vaccination modulates host responses to influenza virus infection that correlate with protection against bacterial superinfection [PDF]

, 2019
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Choi, Angela, Christopoulou, Ioanna, García-Sastre, Adolfo, Saelens, Xavier, Schotsaert, Michael   +4 more
core   +2 more sources

Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]

, 2018
Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico, Belleudi, Francesca, Claudia De Archangelis,, DI FILIPPO, Alessandra, Dionisi, Marco, Napoletano, Chiara, Nuti, Marianna, RAHIMI KOSHKAKI, Hassan, Rughetti, Aurelia, Ruscito, Ilary, Torrisi, Maria Rosaria, Zizzari, ILARIA GRAZIA   +11 more
core   +1 more source

Characterization of Rift Valley fever virus MP-12 strain encoding NSs of Punta Toro virus or sandfly fever Sicilian virus. [PDF]

PLoS Neglected Tropical Diseases, 2013
Rift Valley fever virus (RVFV; genus Phlebovirus, family Bunyaviridae) is a mosquito-borne zoonotic pathogen which can cause hemorrhagic fever, neurological disorders or blindness in humans, and a high rate of abortion in ruminants.
Olga A Lihoradova, Sabarish V Indran, Birte Kalveram, Nandadeva Lokugamage, Jennifer A Head, Bin Gong, Bersabeh Tigabu, Terry L Juelich, Alexander N Freiberg, Tetsuro Ikegami   +9 more
doaj   +1 more source

Characterization of BoHV-1 gG-/tk-/gE- Mutant in Differential Protein Expression, Virulence, and Immunity

Veterinary Sciences, 2021
Infectious bovine rhinotracheitis (IBR), caused by bovine alphaherpesvirus 1 (BoHV-1), is an important disease affecting cattle worldwide resulting in great economic losses.
Marawan A. Marawan, Mingliang Deng, Chen Wang, Yingyu Chen, Changmin Hu, Jianguo Chen, Xi Chen, Huanchun Chen, Aizhen Guo   +8 more
doaj   +1 more source

Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. [PDF]

, 2020
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells.
Amara, Rama R, Beck, Zoltan, Dinasarapu, Ashok R, Elizaldi, Sonny R, Foehl, David H, Forthal, Donald N, Gach, Johannes S, Iyer, Smita S, Kozlowski, Pamela A, LaBranche, Celia C, Lakshmanappa, Yashavanth Shaan, Matyas, Gary R, Nguyen, Nancy K, Rane, Niharika N, Rao, Mangala, Reimann, Keith A, Schmidt, Brian A, Shen, Xiaoying, Tomaras, Georgia D, Trinh, Hung V, Verma, Anil, Walter, Korey A   +21 more
core  

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

The need for more holistic immune profiling in next-generation SARS-CoV-2 vaccine trials

Frontiers in Immunology, 2022
First-generation anit-SARS-CoV-2 vaccines were highly successful. They rapidly met an unforeseen emergency need, saved millions of lives, and simultaneously eased the burden on healthcare systems worldwide. The first-generation vaccines, however, focused
Robert L. Murphy, Robert L. Murphy, Eustache Paramithiotis, Scott Sugden, Todd Chermak, Bruce Lambert, Damien Montamat-Sicotte, John Mattison, Steve Steinhubl   +8 more
doaj   +1 more source

Assessment of Different Infectious Bovine Rhinotracheitis Marker Vaccines in Calves

Vaccines, 2022
Three commercially available infectious bovine rhinotracheitis (IBR) live marker vaccines were evaluated for their ability to provide clinical protection to vaccinated calves against wild-type (wt) Bovine alphaherpesvirus-1 (BoHV-1) challenge and their possible effect on wt BoHV-1 latency reactivation following the challenge.
Stefano Petrini, Alessandra Martucciello, Cecilia Righi, Giovanna Cappelli, Claudia Torresi, Carlo Grassi, Eleonora Scoccia, Giulia Costantino, Cristina Casciari, Roberto Sabato, Monica Giammarioli, Esterina De Carlo, Francesco Feliziani   +12 more
openaire   +3 more sources