Results 181 to 190 of about 403,541 (266)

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

A holistic approach for quantifying the value of public health programs: social return on investment (SROI) analysis of a mobile clinic as an example. [PDF]

Front Public Health
Kumar S, Mallett A, Olsen S, Coleman A.
europepmc   +1 more source

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

Advanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu, Hongmin Liu, Long Fan, Huakun Liu, Shixue Dou, Guoxiu Wang, Nana Wang, Zhongchao Bai   +7 more
wiley   +1 more source

Cooperation mode selection and information sharing in a live streaming e-commerce supply chain with traffic data investment. [PDF]

PLoS One
Wang H, Zhu A, Yu L, Mu D, Meng Z.
europepmc   +1 more source

Transparent Photothermal Slippery Surface Based on Monolayer Self‐Assembled MXene Film for Anti‐Fogging and De‐Icing

Advanced Science, EarlyView.
The ultrathin (2.5 nm) MXene film self‐assembled at liquid interfaces breaks the trade‐off between transparency (82.5 %) and photothermal conversion effect (DT∼25.1°C ± 2.9 °C) under 100 mW cm−2. After encapsulated by a slippery surface with low adhesion, this transparent film can be applied in smart windows, eyewear, and optical sensors to autonomous ...
Xiao Han, Yiming Xie, Mingjia Sun, Di Zhao, Kesong Liu, Liping Heng, Lei Jiang   +6 more
wiley   +1 more source

Analysis of market equilibrium based on overconfidence behavior of market makers. [PDF]

PLoS One
Wang R, Wang J, Yang Z.
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Farmers' willingness to pay for organic fertilisers from Black Soldiers Fly Larvae frass in Malawi. [PDF]

Discov Sustain
Mnthambala F, Tembo K, Chitete MMN, Moyo N, Phiri AT, Peguero DA, Zurbrügg C.   +6 more
europepmc   +1 more source

Boosting Fast‐Charging Performance of Ni‐Rich NCM9055 Cathodes with Nb2O5 Dual Functional Modification

Advanced Science, EarlyView.
A dual‐functional Nb2O5 modulation strategy is reported to overcome kinetic limitations in Ni‐rich cathodes. The formation of LiNbO3 phase at the grain boundary of the polycrystalline NCM9055 cathode preserves a radially aligned microstructure and establishes fast lithium‐ion pathways.
Tian Rao, Zhaowen Bai, Jian Wang, Yang Ren, Qingsong Weng, Zhongzhu Liu, Maxim Avdeev, Robson Monteiro, Luanna Parreira, Xuejie Huang, Guohua Chen, Yongming Zhu   +11 more
wiley   +1 more source

Net Present Value Impact of FDA's Phase 3 Waivers on Monoclonal Antibody Biosimilar Development. [PDF]

Biologics
Ranbhor R, Kulkarni P.
europepmc   +1 more source