Results 21 to 30 of about 3,818,655 (309)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Methods of Calculating the Indexes of Intellectual Capital of Organizations

open access: yesСтатистика и экономика, 2023
Competitive functioning at the micro and macro levels of businesses in different industries creates the need to make changes in the assessment of the impact on the performance of companies of tangible and intangible assets, leading to an increase in the ...
V. A. Korzhak
doaj   +1 more source

Easement Condemnation and State v. Doyle: Fair Market Value without a Market [PDF]

open access: yes, 1989
Rapporten presenterar ett tillvägagångssätt att med moderna medel angripa en av äldre tidens kryptotekniker, bokchiffer, där nummer utifrån boktexter utgör kryptotexten.
Krogh, Robert, Nyberg, Sofia
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Comparison of the public health impact of RSV disease prevention options for infants: a static decision model of the US birth cohort

open access: yesExpert Review of Vaccines
Background In the U.S.A. three prophylactic interventions are approved for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD) in infants: nirsevimab and clesrovimab (extended half-life monoclonal antibodies) and ...
Alexia Kieffer   +14 more
doaj   +1 more source

Problems with the Income Value Basis in Agricultural Lands Subject to Inheritance

open access: yesİstanbul Hukuk Mecmuası, 2023
Agreement among heirs is essential when divvying up inherited agricultural lands. If the heirs cannot agree, the problem is resolved through litigation. In accordance with Article 657/II of Turkish Civil Code No. 4721 and Article 8/C of Law No.
Sümeyye Tuba Korkusuz
doaj   +1 more source

Market Value [PDF]

open access: yes, 2015
MARKET VALUE is a collection of stories about people in Southwest Florida struggling to make sense of their lives when faced with shifting economic realities.
Morando, Christine
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Indirect Comparison of PCV20 Immunogenicity with PCV10 in Pediatric 3 + 1 and 2 + 1 Schedules

open access: yesInfectious Diseases and Therapy
Introduction The 20-valent pneumococcal conjugate vaccine (PCV20) was licensed for prevention of pneumococcal disease in infants and children on the basis of immunogenicity compared with PCV13.
Eileen M. Dunne   +9 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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