Results 101 to 110 of about 116,111 (309)
Clinical Pharmacology &Therapeutics, EarlyView.Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich +5 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin +6 more
wiley +1 more source
TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data
Cytometry Part A, EarlyView.TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou +2 more
wiley +1 more source
Ecography, EarlyView.Species diversity typically increases from higher to lower latitudes, but the regional‐scale variation along this geographic gradient remains unclear. It has been suggested that species diversity throughout Amazonia generally increases westward toward the Andes, but this pattern and its environmental determinants require further investigation for most ...
Pilar L. Maia‐ Braga +14 more
wiley +1 more source
PREDICTIVE GREY MARKOV CHAIN MODEL FOR PITTING CORROSION IN PIPLINES
Jixie qiangdu, 2016 Based on the Grey theory and Markov Chain theory,two prediction models were built,they are Grey Markov Chain prediction model based on absolute distribution（ GMCAD） and Grey Markov Chain prediction model based on probability summation（ GMCPS）.
YU ShuRong, HAN JunYu, LI ShuXin
doaj
Large deviations conditioned on large deviations I: Markov chain and Langevin equation [PDF]
, 2019 Bernard Derrida, Tridib Sadhu
openalex +1 more source
Twenty years of dynamic occupancy models: a review of applications and look to the future
Ecography, EarlyView.Since their introduction over 20 years ago, dynamic occupancy models (DOMs) have become a powerful and flexible framework for estimating species occupancy across space and time while accounting for imperfect detection. As their popularity has increased and extensions have further expanded their capabilities, DOMs have been applied to increasingly ...
Saoirse Kelleher +3 more
wiley +1 more source
Probabilistic spinning reserve adequacy evaluation for generating systems using an Markov chain Monte Carlo‐integrated cross‐entropy method [PDF]
, 2015 Yue Wang
openalex +1 more source