Results 131 to 140 of about 419,601 (272)
The Strong Law of Large Numbers for a Class of Markov Chains [PDF]
Leo Breiman
openalex +1 more source
Slow Expectation–Maximization Convergence in Low‐Noise Dynamic Factor Models
ABSTRACT This paper addresses the slow convergence of the expectation–maximization (EM) algorithm in the estimation of low‐noise dynamic factor models, commonly used in macroeconomic nowcasting and forecasting. We show analytically and in Monte Carlo simulations how the EM algorithm stagnates in a low‐noise environment, leading to inaccurate estimates ...
Daan Opschoor, Dick van Dijk
wiley +1 more source
Abstract Valemetostat is a dual inhibitor of EZH2/1 approved in Japan for the treatment of relapsed/refractory (R/R) adult T–cell lymphoma/leukemia (ATLL) and R/R peripheral T–cell lymphoma (PTCL). It is administered orally once daily (QD) at 200 mg. Here, we present comprehensive population pharmacokinetic (PPK) and exposure–response (ER) analyses of ...
Hiroyuki Inoue +7 more
wiley +1 more source
Last‐minute coordination: Adapting to demand to support last‐mile operations
Abstract In the highly competitive e‐commerce industry, customer‐facing warehouses are crucial as the “order penetration points” for e‐commerce last‐mile operations. This research examines how warehouses use last‐minute coordination, an unstructured mechanism, to ensure sufficient inventory at the order penetration points. Previous research has focused
Kedong Chen +3 more
wiley +1 more source
ABSTRACT Future projections of climate change in the subtropics suggest warming and drying, while evidence from warm periods in the past shows increases in subtropical temperatures and precipitation. Eastern Australia is subject to interannual hydroclimate drivers and has experienced extreme flooding and droughts in recent years.
Joan Macalalad +5 more
wiley +1 more source
Quantifying the 'end of history' through a Bayesian Markov-chain approach. [PDF]
Klimm F.
europepmc +1 more source
ABSTRACT Start‐up CEOs are usually more aligned with the interests of the venture board compared to CEOs in legacy firms, and therefore it is usual to conclude that the traditional agency problem is lower in ventures. In this article, it is argued that this is only half of the story, and that the agency problem is reversed in early ventures such that ...
Glenn Kristiansen
wiley +1 more source

