Results 251 to 260 of about 2,583,540 (350)

Postmarketing Assessment of Antibody–Drug Conjugates: Proof‐of‐Concept Using Model‐Based Meta‐Analysis and a Clinical Utility Index Approach

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Antibody–drug conjugates (ADCs) are a promising class of targeted cancer therapies. However, they need careful dose optimization to maximize effectiveness and minimize side effects. Sometimes, safety issues may only become apparent after approval, so ongoing evaluation is important.
Innocent Gerald Asiimwe   +6 more
wiley   +1 more source

Practical guidelines for Bayesian phylogenetic inference using Markov chain Monte Carlo (MCMC). [PDF]

open access: yesOpen Res Eur, 2023
Barido-Sottani J   +4 more
europepmc   +1 more source

Quantum‐Noise‐Driven Generative Diffusion Models

open access: yesAdvanced Quantum Technologies, EarlyView.
Diffusion Models (DMs) are today a very popular class of generative models for Machine Learning (ML), using a noisy dynamics to learn an unknown density probability of a finite set of samples in order to generate new synthetic data. This study proposes a method to generalize them into the quantum domain by introducing and investigating what are termed ...
Marco Parigi   +2 more
wiley   +1 more source

A Model for Sustainable Development in Territorial Production Systems

open access: yesSustainable Development, EarlyView.
ABSTRACT The territorial production system demand innovation and adaptability to provide the majority of decisions, especially when splitting up available resources among productive sectors by the lens of sustainable development. The system's economic units evolve in dimensional profile, technical execution, and management of productive process to ...
Francesco Sica   +2 more
wiley   +1 more source

Implementation of a practical Markov chain Monte Carlo sampling algorithm in PyBioNetFit. [PDF]

open access: yesBioinformatics, 2022
Neumann J   +8 more
europepmc   +1 more source

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