Results 121 to 130 of about 85,479 (297)

Sequential Monte Carlo samplers with independent Markov chain Monte Carlo proposals

open access: yes, 2018
Sequential Monte Carlo (SMC) methods for sampling from the posterior of static Bayesian models are flexible, parallelisable and capable of handling complex targets.
South, Leah F.   +2 more
core   +1 more source

Waves of range dynamics and gene flow characterize the biogeographic history of Litsea elongata, a dominant tree in East Asian evergreen broadleaved forests

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Evergreen broadleaved forests (EBLFs) represent an iconic vegetation type in subtropical montane East Asia, but they are experiencing intensifying anthropogenic pressure and increasing habitat fragmentation. Here, using a dominant and widespread tree species characteristic of East Asian EBLFs, we examine its phylogeographic history and evaluate what it
Sheng‐Yuan Qin   +7 more
wiley   +1 more source

Computing Densities: A Conditional Monte Carlo Estimator [PDF]

open access: yes
We propose a generalized conditional Monte Carlo technique for computing densities in economic models. Global consistency and functional asymptotic normality are established under ergodicity assumptions on the simulated process.
Huiyu Li   +2 more
core   +2 more sources

Maximum likelihood parameter estimation for latent variable models using sequential Monte Carlo [PDF]

open access: yes
We present a sequential Monte Carlo (SMC) method for maximum likelihood (ML) parameter estimation in latent variable models. Standard methods rely on gradient algorithms such as the Expectation- Maximization (EM) algorithm and its Monte Carlo variants.
Davy, Manuel   +2 more
core   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

open access: yesPest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King   +6 more
wiley   +1 more source

Maximum Working Likelihood Inference with Markov Chain Monte Carlo

open access: yes, 2007
this paper, we describe a method for obtaining frequency based maximum working likelihood (MWL) inference in the presence of missing data which does not require integration of the conditional likelihood.
Daode Huang   +3 more
core  

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre   +5 more
wiley   +1 more source

Implementation of a practical Markov chain Monte Carlo sampling algorithm in PyBioNetFit. [PDF]

open access: yesBioinformatics, 2022
Neumann J   +8 more
europepmc   +1 more source

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