Results 71 to 80 of about 2,604,808 (287)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Sustainability Challenges to the Steel Industry in a Developing Country: Sanctions and Security Issues at the Forefront

Business Strategy and the Environment, EarlyView.
ABSTRACT This article contributes to sustainability research by investigating the complex, geopolitically induced challenges faced by industrial supply chains under international sanctions. Using Iran's steel industry as a case, it examines sustainability barriers through the lens of stakeholder theory. A mixed methods approach was employed.
Seyed Hamed Moosavirad, Mohammad Moshtari, Ali Esfahbodi   +2 more
wiley   +1 more source

Sample caching Markov chain Monte Carlo approach to boson sampling simulation

New Journal of Physics, 2020
Boson sampling is a promising candidate for quantum supremacy. It requires to sample from a complicated distribution, and is trusted to be intractable on classical computers.
Yong Liu, Min Xiong, Chunqing Wu, Dongyang Wang, Yingwen Liu, Jiangfang Ding, Anqi Huang, Xiang Fu, Xiaogang Qiang, Ping Xu, Mingtang Deng, Xuejun Yang, Junjie Wu   +12 more
doaj   +1 more source

Evaluation of Circular Pathways for Heavy‐Duty Vehicle Batteries in Europe Using a Multi‐Method Simulation Approach

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular battery strategies have become of major interest focusing on material availability while increasing economic and environmental benefits. In this context of circular economy, one main challenge for automotive original equipment manufacturers is that the most profitable handling strategy along the lifecycle is unknown.
Michael Lieder, Farazee Mohammad Abdullah Asif, Amir Rashid   +2 more
wiley   +1 more source

Markov Chain Monte Carlo Technology [PDF]

In the past fifteen years computational statistics has been enriched by a powerful, somewhat abstract method of generating variates from a target probability distribution that is based on Markov chains whose stationary distribution is the probability ...
Chib, Siddhartha
core  

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Reweighting Scheme for the Calculation of Grand‐Canonical Expectation Values in Quantum Monte Carlo Simulations With a Fermion Sign Problem

Contributions to Plasma Physics, EarlyView.
ABSTRACT Ab initio path integral Monte Carlo (PIMC) simulations constitute the gold standard for the estimation of a broad range of equilibrium properties of a host of interacting quantum many‐body systems spanning a broad range of conditions from ultracold atoms to warm dense quantum plasmas.
Paul Hamann, Jan Vorberger, Tobias Dornheim   +2 more
wiley   +1 more source

Density estimators through Zero Variance Markov Chain Monte Carlo [PDF]

A Markov Chain Monte Carlo method is proposed for the pointwise evaluation of a density whose normalizing constant is not known. This method was introduced in the physics literature by Assaraf et al (2007).
Daniele Imparato, Antonietta Mira
core  

Evidence of Free‐Bound Transitions in Warm Dense Matter and Their Impact on Equation‐of‐State Measurements

Contributions to Plasma Physics, EarlyView.
ABSTRACT Warm dense matter (WDM) is now routinely created and probed in laboratories around the world, providing unprecedented insights into conditions achieved in stellar atmospheres, planetary interiors, and inertial confinement fusion experiments.
M. P. Böhme, L. B. Fletcher, A. D. Baczewski, H. M. Bellenbaum, Z. A. Moldabekov, J. Vorberger, D. A. Chapman, M. J. MacDonald, S. Schwalbe, T. R. Preston, D. Kraus, T. Gawne, F. R. Graziani, S. Hamel, T. Döppner, T. Dornheim   +15 more
wiley   +1 more source

Schedules of lectures and Monte Carlo method

Lietuvos Matematikos Rinkinys, 2011
In this paper the problem of the construction of schedule of lectures is considered. The Markov chain Monte Carlo method is used. A particular program based on simulated annealing algorithm was created.
Nikolaj Grigorjev, Gediminas Stepanauskas   +1 more
doaj   +1 more source