Results 101 to 110 of about 65,379 (309)
Clinical Pharmacology &Therapeutics, EarlyView.Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich +5 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin +6 more
wiley +1 more source
Markov chains as a proxy for the predictive memory representations underlying mismatch negativity. [PDF]
Front Hum Neurosci, 2023 Schröger E, Roeber U, Coy N.
europepmc +1 more source
TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data
Cytometry Part A, EarlyView.TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou +2 more
wiley +1 more source
Multi-Dimensional Markov Chains of M/G/1 Type
MathematicsWe consider an irreducible discrete-time Markov process with states represented as (k, i) where k is an M-dimensional vector with non-negative integer entries, and i indicates the state (phase) of the external environment.
Valeriy Naumov, Konstantin Samouylov
doaj +1 more source
Improving models for student retention and graduation using Markov chains. [PDF]
PLoS One, 2023 Tedeschi MN +4 more
europepmc +1 more source
Ecography, EarlyView.Species diversity typically increases from higher to lower latitudes, but the regional‐scale variation along this geographic gradient remains unclear. It has been suggested that species diversity throughout Amazonia generally increases westward toward the Andes, but this pattern and its environmental determinants require further investigation for most ...
Pilar L. Maia‐ Braga +14 more
wiley +1 more source
Large deviations conditioned on large deviations I: Markov chain and Langevin equation [PDF]
, 2019 Bernard Derrida, Tridib Sadhu
openalex +1 more source