Results 121 to 130 of about 771,482 (302)
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Breaking point: Identifying the factors that predict suspension from school
British Educational Research Journal, EarlyView.Abstract School suspensions are associated with adverse educational and psychosocial outcomes, yet little is known about how structural disadvantage, relational factors, health behaviours, well‐being indicators and school‐level factors jointly predict suspension risk in England.
Stephanie Cahill +5 more
wiley +1 more source
Multi-Dimensional Markov Chains of M/G/1 Type
MathematicsWe consider an irreducible discrete-time Markov process with states represented as (k, i) where k is an M-dimensional vector with non-negative integer entries, and i indicates the state (phase) of the external environment.
Valeriy Naumov, Konstantin Samouylov
doaj +1 more source
CoRRMotivated by techniques developed in recent progress on lower bounds for sublinear time algorithms (Behnezhad, Roghani and Rubinstein, STOC 2023, FOCS 2023, and STOC 2024) we introduce and study a new class of randomized algorithmic processes that we call Markov Chains with Rewinding. In this setting, an algorithm interacts with a (partially observable)
Amir Azarmehr +3 more
openaire +2 more sources
Convergence, Rank Reduction and Bounds for the Stationary Analysis of Markov Chains
, 2004 We introduce a rank reduction method for computing stationary distributions of Markov chains for which low-rank iteration matrices can be formed. We first prove that, for an irreducible Markov chain, a necessary and sufficient condition for convergence ...
Peng, Bin
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT Autologous cell therapy (AuCT) manufacturing networks must balance two competing objectives: reducing cost and improving patient access to time‐sensitive therapy. This study compares three AuCT manufacturing network designs: a centralized network with a single manufacturing facility, a coordinated point‐of‐care (POC) network in which POCs can ...
Zhaowei Li +3 more
wiley +1 more source
A parallel block projection method of the Cimmino type for finite Markov chains
, 1995 A parallel block projection method is used to approximate the stationary vector of a finite Markov chain. Block projection methods are very attractive for solving large chains thanks to their potential for parallel computation and robustness.
Sgallari F, Spaletta Giulia, Benzi M
core +1 more source
Markov Chain Monte Carlo Technology [PDF]
In the past fifteen years computational statistics has been enriched by a powerful, somewhat abstract method of generating variates from a target probability distribution that is based on Markov chains whose stationary distribution is the probability ...
Chib, Siddhartha
core
Business Strategy and the Environment, EarlyView.ABSTRACT This article contributes to sustainability research by investigating the complex, geopolitically induced challenges faced by industrial supply chains under international sanctions. Using Iran's steel industry as a case, it examines sustainability barriers through the lens of stakeholder theory. A mixed methods approach was employed.
Seyed Hamed Moosavirad +2 more
wiley +1 more source
ESG Controversies in Global Firms: A Black Mark?
Business Strategy and the Environment, EarlyView.ABSTRACT Despite increasing attention paid by companies to sustainability, there is still evidence of environmental, social and governance (commonly referred to as ESG) scandals. As research on this topic is scant, this paper aims to analyse the impact of ESG controversies on firms' sustainability practices, that is, ESG policies, as well as ...
Beatrice Bais, Guido Orzes, Marco Sartor
wiley +1 more source