Results 31 to 40 of about 192,524 (234)

Perturbation theory for Markov chains via Wasserstein distance

open access: yes, 2017
Perturbation theory for Markov chains addresses the question how small differences in the transitions of Markov chains are reflected in differences between their distributions.
Rudolf, Daniel, Schweizer, Nikolaus
core   +1 more source

A Markov Chain Model Checker [PDF]

open access: yes, 2000
Markov chains are widely used in the context of performance and reliability evaluation of systems of various nature. Model checking of such chains with respect to a given (branching) temporal logic formula has been proposed for both the discrete [17,6 ...
Hermanns, Holger   +3 more
core   +5 more sources

Attainability for Markov and Semi-Markov Chains

open access: yesMathematics
When studying Markov chain models and semi-Markov chain models, it is useful to know which state vectors n, where each component ni represents the number of entities in the state Si, can be maintained or attained.
Brecht Verbeken, Marie-Anne Guerry
doaj   +1 more source

Markov and Semi-Markov Chains, Processes, Systems, and Emerging Related Fields

open access: yesMathematics, 2021
Probability resembles the ancient Roman God Janus since, like Janus, probability also has a face with two different sides, which correspond to the metaphorical gateways and transitions between the past and the future [...]
P.-C.G. Vassiliou, Andreas C. Georgiou
doaj   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Conditional ergodicity in infinite dimension

open access: yes, 2014
The goal of this paper is to develop a general method to establish conditional ergodicity of infinite-dimensional Markov chains. Given a Markov chain in a product space, we aim to understand the ergodic properties of its conditional distributions given ...
Tong, Xin Thomson, van Handel, Ramon
core   +1 more source

An estimate for an expectation of the simultaneous renewal for time-inhomogeneous Markov chains

open access: yesModern Stochastics: Theory and Applications, 2016
In this paper, we consider two time-inhomogeneous Markov chains ${X_{t}^{(l)}}$, $l\in \{1,2\}$, with discrete time on a general state space. We assume the existence of some renewal set C and investigate the time of simultaneous renewal, that is, the ...
Vitaliy Golomoziy
doaj   +1 more source

Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations

open access: yesAdvanced Science, EarlyView.
Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl   +7 more
wiley   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

open access: yesAdvanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang   +12 more
wiley   +1 more source

Spectrum of stochastic adding machines and fibered Julia sets

open access: yes, 2012
Consider the basic algorithm to perform the transformation n--> n+1 changing digits of the d-adic expansion of n one by one. We obtain a family of Markov chains on the non-negative integers through sucessive and independent applications of the algorithm ...
Messaoudi, Ali   +2 more
core   +4 more sources

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