Clinical Pharmacology &Therapeutics, EarlyView.Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke +12 more
wiley +1 more source
Markov Decision Process-Based Personalized Follow-Up Planning for Type 2 Diabetes: Retrospective Cohort Study. [PDF]
JMIR Med InformChen S +5 more
europepmc +1 more source
Reduced size of larvae and small fish linked to warming and reduced prey density
Ecography, EarlyView.Body size is an integrative trait that has declined across many ecological assemblages in the last decades. Changes in body size of early life stages and small‐bodied fish are driven by complex interactions between size‐dependent mortality, and temperature‐ and food‐dependent growth, and can have consequences for recruitment to the adult stock and food
Max Lindmark +6 more
wiley +1 more source
Management insulin dosing for diabetes using a partially observable Markov decision process with missing data imputation. [PDF]
Sci RepXiang J, Yu H, Luo L, Liu S.
europepmc +1 more source
Stability conditions for a Piecewise Deterministic Markov Process [PDF]
In the present paper we study the stability of a threshold continuos-time model that belongs to the class of Piecewise Deterministic Markov Processes. We derive a sufficient condition on the coefficients of the model to ensure the exponential ergodicity ...
Fonseca Giovanni
core
From patterns to predictions: a framework for the spatial epidemiology of wildlife diseases
Ecography, EarlyView.Wildlife diseases pose a significant threat to biodiversity conservation, public health, and livestock. Spatial epidemiology provides a robust framework to understand disease dynamics and guide policy and management. However, the rapid proliferation of spatial methods has largely occurred in isolation across disciplines, leaving the field without a ...
Cesar Herraiz, Pelayo Acevedo
wiley +1 more source
Economic evaluation of a digital symptom checker for endometriosis using a Markov decision process model. [PDF]
NPJ Digit MedXu Y +9 more
europepmc +1 more source
On Markov Chains with Uncertain Data [PDF]
In this paper, a general method is described to determine uncertainty intervals for performance measures of Markov chains given an uncertainty region for the parameters of the Markov chains.
Blanc, J.P.C., Hertog, D. den
core
Species traits mediate terrestrial mammal density responses to human impacts
Ecography, EarlyView.Human activities are reshaping ecosystems, but their effects on species population density remain poorly understood. Most studies focus on species presence–absence, thus limiting insight into how anthropogenic pressures affect population density. Emerging evidence suggests that responses of natural populations to human disturbance are highly variable ...
Luca Santini +13 more
wiley +1 more source
Predicting connectivity from movement trajectories and step selection
Ecography, EarlyView.Predicting and mapping connectivity are essential for ecology and conservation in the face of environmental change. Yet connectivity modeling is challenging because it requires understanding how organisms successfully move across complex landscapes.
Robert J. Fletcher Jr +8 more
wiley +1 more source