Results 91 to 100 of about 725,754 (336)
Tiotropium bromide in the routine care of GOLD stage II COPD patients: a pharmaeconomic evaluation
Farmeconomia: Health Economics and Therapeutic Pathways, 2011 Background: a secondary pre-specified analysis of the UPLIFT cohort demonstrated that the inclusion of tiotropium bromide in the routine care of GOLD stage II (moderate) chronic obstructive pulmonary disease (COPD) patients is associated with stronger ...
Orietta Zaniolo +2 more
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International Journal of Preventive Medicine, 2020 Background: Today, cardiovascular disease is one of the main causes of mortality and disability in most developed and developing countries. The prediction of the major causes of deaths all over the world at all ages shows that 61% of deaths are due to ...
Alireza Jabbari +3 more
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Painting Peptides With Antimicrobial Potency Through Deep Reinforcement Learning
Advanced Science, EarlyView.AMPainter is a powerful design model for ’painting’ the antimicrobial potency on any given peptide sequence, based on the strategy of virtual directed evolution and deep reinforcement learning. Abstract In the post‐antibiotic era, antimicrobial peptides (AMPs) are considered ideal drug candidates because of their lower likelihood of inducing resistance.
Ruihan Dong, Qiushi Cao, Chen Song
wiley +1 more source
Modeling stochastic gene expression: From Markov to non-Markov models
Mathematical Biosciences and Engineering, 2020 Gene expression is an inherently noisy process due to low copy numbers of mRNA or protein. The involved reaction events may happen in a Markov fashion but also in a non-Markov manner, depending on waiting-time distributions for the occurrence of reaction events.
Jia Jun Zhang +4 more
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Misspecified Markov Switching Model [PDF]
I characterize the local power of an optimal test for a Markov Switching model under generalized alternatives. The result shows that the test still has power for the model with endogenous stochastic parameters unless they are orthogonal to the score ...
Youngki Shin
core
Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition
Advanced Science, EarlyView.This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang +3 more
wiley +1 more source
Markov models in cardiac surgery
Journal of Cardiac Surgery, 2020 Spinal cord ischemia remains a dreadful complication after thoracoabdominal aortic aneurysm repair. The role of cerebrospinal fluid drain in such patients needs further clarifications. Tam and colleagues carried out an interesting decision analysis study that supports the routine use of the cerebrospinal fluid drain after thoracoabdominal aneurysm ...
Marco Moscarelli +2 more
openaire +4 more sources
BROAD‐NESS Uncovers Dual‐Stream Mechanisms Underlying Predictive Coding in Auditory Memory Networks
Advanced Science, EarlyView.BROADband Network Estimation via Source Space (BROAD‐NESS) is a flexible analytical pipeline for identifying large‐scale brain networks from event‐related, source‐reconstructed MEG data, with a focus on auditory predictive and memory processes. BROAD‐NESS integrates a suite of complementary tools, including PCA‐based decomposition, phase space, and ...
Leonardo Bonetti +8 more
wiley +1 more source
STEMDiff: A Wavelet‐Enhanced Diffusion Model for Physics‐Informed STEM Image Generation
Advanced Science, EarlyView.STEMDiff, which is a conditional diffusion model that generates realistic STEM images from crystal structure‐derived binary labels, is proposed, overcoming high‐frequency bias via a Discrete Wavelet Transform‐based architecture. It produces experimentally indistinguishable images, enabling annotation‐free training of networks for precise atomic ...
Yihui Bao +4 more
wiley +1 more source
International Journal of COPD, 2020 Bhavesh Lakhotia,1 Ronan Mahon,1 Florian S Gutzwiller,2 Andriy Danyliv,1 Ivan Nikolaev,2 Praveen Thokala3 1Novartis Ireland Limited, Dublin, Ireland; 2Novartis Pharma, Basel, AG, Switzerland; 3PT Health Economics Ltd, Sheffield, UKCorrespondence: Ronan ...
Lakhotia B +5 more
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