Results 81 to 90 of about 725,754 (336)

Perturbation theory for Markov chains via Wasserstein distance

, 2017
Perturbation theory for Markov chains addresses the question how small differences in the transitions of Markov chains are reflected in differences between their distributions.
Rudolf, Daniel, Schweizer, Nikolaus
core   +1 more source

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

Advanced Science, EarlyView.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng, Hua Wang, Li Zhang, Shiping Li, Yuan Yuan, Mengting Tian, Yi Qu, Junjie Ying, Meicen Zhou, Yong Hu, Jinglan Huang, Rong Zou, Fengyan Zhao, Xiaojuan Su, Qian Liu, Yan He, Jinxing Feng, Weimin Huang, Ying Luo, Zhemin Zhou, Wei Shen, Dezhi Mu, Shaopu Wang   +22 more
wiley   +1 more source

Impact analysis of expanded access to ketamine for treatment-resistant depression

Journal of Comparative Effectiveness Research
Aim: This study aimed to estimate the economic impacts of expanded access to ketamine relative to electroconvulsive therapy (ECT) by offering intravenous ketamine to US patients with nonpsychotic treatment-resistant depression (TRD) and moderate-to ...
Thanh Lu, Sophia D’Angelo, Zohra Tayebali, Matthew Dempsey, Kristen Giombi, Olga Khavjou   +5 more
doaj   +1 more source

Connecting the latent multinomial

, 2015
Link et al. (2010) define a general framework for analyzing capture-recapture data with potential misidentifications. In this framework, the observed vector of counts, $y$, is considered as a linear function of a vector of latent counts, $x$, such that ...
Bonner, Simon J., Schofield, Matthew R.
core   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Analysis Results of the Regional Registry of Patients with Diffuse Large B-cell Lymphoma: Risk Factors and Chemo-Immunotherapy Issues

Клиническая онкогематология, 2019
Background & Aims. At least one third of patients with diffuse large B-cell lymphoma (DLBCL) are resistant to first-line therapy. R-CHOP chemo-immunotherapy does not yield acceptable results in high-risk patients. Effectiveness of options based either on
KD Kaplanov, NP Volkov, TYu Klitochenko, IV Matveeva, AL Shipaeva, MN Shirokova, NV Davydov, EG Gemdzhian, DS Abramov, DM Konovalov, GL Snigur, NA Red’kina   +11 more
doaj   +1 more source

Jump Markov models and transition state theory: the Quasi-Stationary Distribution approach

, 2016
We are interested in the connection between a metastable continuous state space Markov process (satisfying e.g. the Langevin or overdamped Langevin equation) and a jump Markov process in a discrete state space.
Di Gesù, Giacomo, Lelièvre, Tony, Nectoux, Boris, Peutrec, Dorian Le   +3 more
core   +3 more sources

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

Advanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunil Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr, Michal Hocek, M. Cristina Cardoso   +11 more
wiley   +1 more source

Impact of Human Error Modeling on Failure Rate and Optimum Routine Test Interval of Protection System

Iranian Journal of Electrical and Electronic Engineering, 2021
Power systems should have acceptable reliability in order to operate properly. Highly available and dependable protective relays help to obtain the desirable reliability.
A. Mirsamadi, Y. Damchi, M. Assili
doaj  

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

Advanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu, Sarah Golconda, Ga‐Eun Lee, Dantong Xue, Guillermo Domínguez‐Huerta, James M. Wainaina, Benjamin Bolduc, Shashanka Murthy, Shihyoung Kim, Seth Faith, Shan‐Lu Liu, Jiyoung Lee, Michael Oglesbee, Matthew B Sullivan, Sanggu Kim   +14 more
wiley   +1 more source