Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
A Survey for Deep Reinforcement Learning Based Network Intrusion Detection
This paper surveys deep reinforcement learning (DRL) for network intrusion detection, evaluating model efficiency, minority attack detection, and dataset imbalance. Findings show DRL achieves state‐of‐the‐art results on public datasets, sometimes surpassing traditional deep learning.
Wanrong Yang +3 more
wiley +1 more source
State-specific disruptions of dynamic functional connectivity in young migraine without aura: a hidden Markov model approach. [PDF]
Xu C +10 more
europepmc +1 more source
Continual decision‐making dynamics across biological organisms
ABSTRACT Decision‐making is a central function of adaptive behaviour in biological agents. However, strategies for adaptive decision‐making can vary substantially across species. Here, we aim to extend the comparative scope of decision‐making analyses to phylogenetically diverse organisms.
Liberty Severs, Qiuran Wang
wiley +1 more source
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman +4 more
wiley +1 more source
The potential survival gain and cost-effectiveness of circulating tumor DNA-guided treatment switching in advanced non-small cell lung cancer: A simulation modeling study. [PDF]
Jansen JP, Douglas MP, Phillips KA.
europepmc +1 more source
Artificial Intelligence and Machine Learning Approaches used in Building Energy Analysis, Control, and Provision of Grid Support Services. ABSTRACT Increasing penetrations of variable renewable energy sources like wind and solar photovoltaic (PV) systems are challenging power system stability worldwide.
Jack S. Bryant +11 more
wiley +1 more source
Cost-Utility Analysis of Renal Replacement Therapy Modalities in the Management of Severe Acute Kidney Injury in US Critically Ill Patients. [PDF]
Martins R +4 more
europepmc +1 more source
Recommender Systems: Taxonomy, Applications and Current Research Trends
Integrating taxonomy, application developments, open‐source software, and publication trends, this paper identifies and outlines promising future directions for recommender systems research. ABSTRACT Recommender Systems play an essential role in assisting users to navigate the immense amount of information and services available online, aiding them in ...
Daniel Ranchal‐Parrado +2 more
wiley +1 more source
Multi-adaptive event-triggered consensus of positive multi-agent systems using pinning strategy. [PDF]
Li Q, Dong L, Yang H.
europepmc +1 more source

