Results 31 to 40 of about 8,068 (254)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh   +4 more
wiley   +1 more source

Study on the Dynamic Biological Characteristics of Human Bone Marrow Mesenchymal Stem Cell Senescence

open access: yesStem Cells International, 2019
Objective. To preliminary explore the senescent dynamic changes of the bone marrow mesenchymal stem cells (BMMSCs) by human ageing and its possible mechanism. Methods.
Xiongbin Chen   +8 more
doaj   +1 more source

Lipid composition of normal human bone marrow as determined by column chromatography*

open access: yesJournal of Lipid Research, 1962
The composition of the lipids of normal human bone marrow has been determined. Marrows were obtained post-mortem from the femurs of 12 subjects ranging in age from 1 to 78 years. The total extractable lipid, which varied from 28% to 84% of the tissue wet
Paul K. Lund   +2 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Colony forming assay on 10 months old miR29ab1 knockout bone marrows (n = 8; 4 ko + 4 wt; p = 0.006).

open access: yes, 2015
Colony forming assay on 10 months old miR29ab1 knockout bone marrows (n = 8; 4 ko + 4 wt; p = 0.006).
Lauren Kauffman (765565)   +6 more
core   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Colony forming assay on 6 months old miR29ab1 knockout bone marrows (n = 8; 4 ko + 4 wt; p = 0.01).

open access: yes, 2015
Colony forming assay on 6 months old miR29ab1 knockout bone marrows (n = 8; 4 ko + 4 wt; p = 0.01).
Lauren Kauffman (765565)   +6 more
core   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Percentages and absolute numbers of colony forming units-fibroblasts (CFU-Fs) in sublethally (4Gy) irradiated bone marrows.

open access: yes, 2013
A: 10 days-cultured CFU-Fs colonies stained with May Grünmwald Giemsa (a: original magnification ×50 and b: original magnification ×200). B: Proportion of CFU-Fs in irradiated bone marrows (black columns) compared to controls (grey columns).C: Absolute ...
Chantal Humblet (332380)   +6 more
core   +1 more source

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