Results 41 to 50 of about 8,068 (254)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Colony forming assay on 2 months old miR29ab1 knockout bone marrows (n = 4; 2 WT and 2 KO; p = 0.04).

, 2015
Colony forming assay on 2 months old miR29ab1 knockout bone marrows (n = 4; 2 WT and 2 KO; p = 0.04).
Lauren Kauffman (765565), Ramasamy Santhanam (765569), Veronica Balatti (765566), Frederick Racke (765568), Paolo Fadda (765567), Stefan Costinean (577253), Luciano Cascione (280104)   +6 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

SDF-1 expression in irradiated bone marrows and CFU-Fs.

, 2013
A: Labelling with anti-sdf1 antibodies is more intense in bone marrows from day-1 irradiated mice (Ab) compared to control ones (Aa) (original magnification ×200).
Chantal Humblet (332380), Kimimitsu Oda (332384), Marie-Paule Defresne (332386), Géraldine Poncin (332378), Aurore Beaulieu (332379), Jacques Boniver (91763), Albert Thiry (332382)   +6 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Enabling High Accuracy Dynamic Applications in Urban Environments Using PPP and RTK on Android Multi-Frequency and Multi-GNSS Smartphones

, 2019
In recent months, smartphones and IoT devices have become the leading products of mass-market GNSS. However, they are still limited in their positioning capability and, even with the release of Android raw measurements in late 2016, the use of PPP and ...
Fortunato, Marco, Critchley-Marrows, Joshua, Joshua Critchley-Marrows, Marco Fortunato, Maria Loredana Ivanovici, Benedetti, Elisa, Elisa Benedetti, Ivanovici, Maria Loredana, Roberts, William, Siutkowska, Malgorzata, William Roberts, Malgorzata Siutkowska   +11 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Suppression of magnetization ripple by exchange bias

, 2009
We present a magnetic domain imaging study of polycrystalline exchange biased ferromagnet/antiferromagnet Co/FeMn bilayers using x-ray photoelectron emission microscopy. At low FeMn thicknesses, where the system exhibits no exchange bias, a magnetic fine
Kotsugi M, Marrows CH, Kuch W., Chelaru LI, Hickey BJ, OFFI, FRANCESCO, Ali M, Wang J   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Additional file 12 of Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

, 2022
Additional file 12: Figure S4. Representative immunohistochemical staining images for GSTT1 in bone marrows of Control, Model, S+Rg, S, and Rg ...
Yinxiao Mi (14063437), Xiaoyan Lu (226200), Jing Qian (14063440), Li Liu (75607), Shiyu Zhang (372275), Tingting Ye (644815), Xiaohui Fan (113427)   +6 more
core   +1 more source