Results 91 to 100 of about 1,176,059 (339)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Terrestrial Planet Formation in a protoplanetary disk with a local mass depletion: A successful scenario for the formation of Mars

open access: yes, 2013
Models of terrestrial planet formation for our solar system have been successful in producing planets with masses and orbits similar to those of Venus and Earth. However, these models have generally failed to produce Mars-sized objects around 1.5 AU. The
Haghighipour, N.   +3 more
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Life on Mars [PDF]

open access: yesNature, 1908
IF the canals of Mars are structures made by intelligent beings, it is difficult to believe that these beings have not at their disposal appliances both for construction and survey. It is difficult to believe that some of these appliances are not made of metal. If made of metal, it is difficult to believe that the Martians do not use fire.
openaire   +3 more sources

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

open access: yesFEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran   +6 more
wiley   +1 more source

Water on Mars—A Literature Review

open access: yes, 2020
To assess Mars’ potential for both harboring life and providing useable resources for future human exploration, it is of paramount importance to comprehend the water situation on the planet.
Mohammad Nazari-Sharabian   +3 more
semanticscholar   +1 more source

Saltation transport on Mars

open access: yes, 2007
We present the first calculation of saltation transport and dune formation on Mars and compare it to real dunes. We find that the rate at which grains are entrained into saltation on Mars is one order of magnitude higher than on Earth.
B. White   +11 more
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Mars Orbiter Laser Altimeter: Experiment summary after the first year of global mapping of Mars [PDF]

open access: yes, 2001
The Mars Orbiter Laser Altimeter (MOLA), an instrument on the Mars Global Surveyor spacecraft, has measured the topography, surface roughness, and 1.064-μm reflectivity of Mars and the heights of volatile and dust clouds.
Ivanov, Anton B.   +2 more
core  

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