Results 161 to 170 of about 1,068,414 (309)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Numerical modelling of recent impacts on Mars and contribution to InSight mission science

, 2021
Katarina Miljković, A. Rajšić, Tanja Neidhart, Eleanor K. Sansom, Natalia Wójcicka, G. S. Collins, I. J. Daubar   +6 more
openalex   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Performance modelling of miniaturized flash-imaging lidars for future mars exploration missions [PDF]

, 2017
Valentin Mitev, A. Pollini, Jacques Haesler, J. Pereira do Carmo   +3 more
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Mars : Mariners reach Mars [PDF]

Nature, 1969
openaire   +1 more source

Investigating the Quality of Mobile Apps for Drug-Drug Interaction (DDI) Management using Mobile App Rating Scale (MARS) and K-Means Clustering : Systematic Search in App Stores Analysis (Preprint)

Ayush Bhattacharya, José F. Flórez-Arango   +1 more
openalex   +1 more source

Identification of an uncharacterized gene as a mitochondrial methionine tRNA synthetase in Caenorhabditis elegans. [PDF]

G3 (Bethesda)
Thapa BV, Das M, Taylor DI, Held JP, Patel MR.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Understanding Medication Adherence and Glycaemic Level in People With Type 2 Diabetes Across Countries: A Cross-Sectional and Longitudinal Analysis of Medication Beliefs, Illness Perceptions, Resistance to Illness and Mood. [PDF]

Endocrinol Diabetes Metab
Teo V, Weinman J, Yap KZ, Lopez SE, Hodgkinson A, Chamley M.   +5 more
europepmc   +1 more source