Results 161 to 170 of about 52,598 (262)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Toward "Safe" Chemicals and Materials on Mars: Knowledge Gaps for Expanding Planetary Protection Requirements. [PDF]

Environ Sci Technol
Hader JD, Fairén AG, Ågerstrand M, MacLeod M, Nowack B.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Mars sample return campaign: biological risk and a proposed sample safety assessment protocol. [PDF]

Appl Environ Microbiol
McDonnell G, Teece BL, Mackelprang R, Cressie N, McQuiston JR, Mayhew LE, Steele A, Siljeström S, Ahern BM, Baird N, Davis RE, French KL, Glamoclija M, Graham H, Hummel KB, Page W, Pearce N, Regberg A, Relman D, Sephton MA, Sherwood Lollar B, Vanhomwegen J, Wilhelm MB, Shirey B, Beaty DW.   +24 more
europepmc   +1 more source

ON THE SPECTRUM OF MARS [PDF]

Publications of the Astronomical Society of the Pacific, 1909
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Joint observations by Tianwen-1 and MAVEN: Ushering in a new era of rapid dynamical coupling in the Martian space environment. [PDF]

Innovation (Camb)
Wang Y, Huang S, Lin R, Yuan Z.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Letter to the Editor: Commentary on Validation of the Korean Moss Attention Rating Scale in Traumatic Brain Injury: Reliability and Validity (<i>Korean J Neurotrauma</i> 2026;22:24-35). [PDF]

Korean J Neurotrauma
Kim HR.
europepmc   +1 more source