Results 61 to 70 of about 994,793 (297)

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

A splice donor variant in SLAMF1 is associated with canine atopic dermatitis

open access: yesFrontiers in Veterinary Science
IntroductionCanine atopic dermatitis (CAD) is a common inflammatory skin condition in dogs. It is a lifelong issue that poses a significant welfare concern due to the chronic skin discomfort and pruritus (itching) experienced by affected animals ...
Oliver P. Forman   +13 more
doaj   +1 more source

Cooling of 3D granular gases in microgravity experiments

open access: yesEPJ Web of Conferences, 2017
Granular gases are a most peculiar state, superficially similar to molecular gases: They are loose ensembles of moving grains, rarely interacting with each other and with container walls.
Harth Kirsten   +3 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance
Ancylostoma caninum is the most significant intestinal nematode parasite of dogs. We acquired fecal surveillance data from a large population of dogs in the United States (US). A diagnostic test using real-time PCR (qPCR) for Ancylostoma spp.
Pablo D. Jimenez Castro   +7 more
doaj   +1 more source

Conceptual Architectural Response to Radiation on Mars

open access: yesArchitecture, Civil Engineering, Environment, 2023
The climatic conditions on Mars are significantly different from those on Earth, which is the main factor affecting the potential architectural solutions on this planet. Above all, high levels of cosmic radiation of solar and extragalactic origin require
Malec Tomasz Eugeniusz
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

The mechanism of pyridine hydrogenolysis on molybdenum-containing catalysts : III. Cracking, hydrocracking, dehydrogenation and disproportionation of pentylamine [PDF]

open access: yes, 1974
The conversion of pentylamine on a MoO3-Al2O3 catalyst was studied between 250 and 350 °C, at various hydrogen pressures. The reactions observed were cracking to pentene and ammonia, hydrocracking to pentane and ammonia, dehydrogenation to pentanimine ...
Mars, P., Sonnemans, J.
core   +2 more sources

Global Variations in Water Vapor and Saturation State Throughout the Mars Year 34 Dusty Season [PDF]

open access: hybrid, 2022
James Holmes   +12 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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