Results 51 to 60 of about 965,575 (296)

Martian Atmospheric Tides Revealed From MAVEN/IUVS and MRO/MCS Observations

open access: yesGeophysical Research Letters
Utilizing atmospheric temperature observed from Mars Years 33–36 by the imaging ultraviolet spectrograph (IUVS) onboard the Mars atmosphere and volatile evolution (MAVEN) and Mars climate sounder (MCS) onboard Mars Reconnaissance Orbiter (MRO), we derive
Chengyun Yang   +4 more
doaj   +1 more source

Novel solvent systems for in situ extraterrestrial sample analysis [PDF]

open access: yes, 2010
The life marker chip (LMC) is being designed to test for the chemical signature of life in the soil and rocks of Mars. It will use an antibody array as part of its detection and characterisation system and aims to detect both polar and non-polar ...
Baki, Alexander O.   +9 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Sintering of ceramics for clay in situ resource utilization on Mars

open access: yesOpen Ceramics, 2020
The sintering of wet processed Mars global simulant green bodies is explored. Green bodies shaped using slip casting, throwing on a potter’s wheel and additive manufacturing, including material extrusion (robocasting) and layerwise slurry deposition (LSD)
David Karl   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Earth – Mars Similarity Criteria for Martian Vehicles [PDF]

open access: yesINCAS Bulletin, 2010
In order to select the most efficient kind of a martian exploring vehicle, the similarity criteria are deduced from the equilibrium movement in the terrestrial and martian conditions.
Octavian TRIFU, George SAVU
doaj   +1 more source

The Atmosphere of Mars

open access: yesThe Astrophysical Journal, 1926
Martian atmosphere examined through its redness, its albedo and its surface markings, noting also the composition of its two layers of particulate ...
openaire   +1 more source

Identifying and Interpreting Stratification in Sedimentary Rocks on Mars: Insight from Rover and Orbital Observations and Terrestrial Field Analogs [PDF]

open access: yes, 2013
Sedimentary rocks on Mars provide insight into past aqueous and atmospheric processes, climate regimes, and potential habitability. The stratigraphic architecture of sedimentary rocks on Mars is similar to that of Earth, indicating that the processes ...
Edgar, Lauren Ashley
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

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