Results 61 to 70 of about 113,191 (310)

Large Dust Aerosol Sizes Seen During the 2018 Martian Global Dust Event by the Curiosity Rover

Geophysical Research Letters, 2019
Mars' atmosphere typically supports dust aerosol with an effective radius near 1.5 μm, varying from ~1 μm during low dust times near northern summer solstice to ~2 μm during higher dust times in southern spring and summer.
M. T. Lemmon, S. D. Guzewich, T. McConnochie, A. deVicente‐Retortillo, G. Martínez, Michael D. Smith, J. F. Bell III, D. Wellington, S. Jacob   +8 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Nitrogen Fixation at Paleo‐Mars in an Icy Atmosphere

Geophysical Research Letters
Recent findings of NO near Gale Crater on Mars have been explained by two pathways: formation of nitric acid (HNO3) in a warm climate or formation of peroxynitric acid (HO2NO2) in a cool climate.
Danica Adams, Armin Kleinböhl, King‐Fai Li, Franklin P. Mills, Run‐Lie Shia, Robin Wordsworth, Yuk L. Yung   +6 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Effects of the 2018 Martian Global Dust Storm on Boundary Positions in the Induced Magnetosphere

The Planetary Science Journal
Global dust storms at Mars have a significant impact on the atmosphere and ionosphere, but only recently has their impact on the magnetosphere been investigated.
Catherine E. Regan, Andrew J. Coates, Mark Lester, Anne Wellbrock, Geraint H. Jones, Beatriz Sánchez-Cano, Philippe Garnier, Louisa J. Preston, František Němec, Václav Linzmayer, Rudy A. Frahm, Mats Holmström   +11 more
doaj   +1 more source

Breeding vectors and predictability in the Oxford Mars GCM [PDF]

, 2003
A breeding vectors approach is used to study the intrinsic predictability of the Martian atmosphere using the Oxford Mars General Circulation Model (MGCM).
Lewis, S.R., Newman, C.E., Read, P.L.
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A Simple Subgrid‐Scale Model for Slope Winds on Mars

Earth and Space Science
Global Climate Models (GCMs) are useful tools for simulating the dynamics of Mars atmosphere on a planetary scale. However their coarse resolution (∼100 km) does not allow to capture small‐scale phenomena such as slope winds which can occur over scales ...
T. Pierron, F. Forget, E. Millour, A. Spiga, A. Martinez   +4 more
doaj   +1 more source

Volatiles on Mars [PDF]

The long-term evolution of both the atmosphere and the surface of Mars can be understood by examining the history of volatiles in the Mars atmosphere, their non-atmospheric reservoirs, and the processes of exchange between the two.
Jakosky, Bruce M.
core   +1 more source