Results 61 to 70 of about 140,234 (311)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Life, 2018 The acidic sulfate-rich waters of the Meridiani Planum region were potentially a habitable environment for iron-oxidizing bacteria on ancient Mars. If life existed in this ancient martian environment, jarosite minerals precipitating in these waters may ...
Liane Loiselle +5 more
doaj +1 more source
Review of Key Technologies of Rotary-Wing Mars UAVs for Mars Exploration
Inventions, 2023 The sparse atmosphere on the surface of Mars provides the necessary flight conditions for Mars unmanned aerial vehicles (UAVs) to perform low-altitude flights.
Pengyue Zhao +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Survey on Unmanned Aerial Vehicle for Mars Exploration: Deployment Use Case
Drones, 2021 In recent years, the area of Unmanned Aerial Vehicles (UAVs) has seen rapid growth. There has been a trend to build and produce UAVs that can carry out planetary exploration throughout the past decade.
Manjula Sharma +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Hanggong uju uihakoeji, 2022 For Mars exploration, spaceflight is advancing with the goal of sending manned spacecraft to Mars. Mars is 54.6 million kilometers away when it is closest to Earth.
Yongwoong Lee
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Small Mars Mission Architecture Study
Advances in Astronomy, 2021 While the vast majority of ESA’s funding for Mars exploration in the 2020s is planned to be invested in ExoMars and Mars Sample Return, there is an interest to assess the possibility of implementing a small mission to Mars in parallel with, or soon after,
Claire E. Parfitt +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source