Results 121 to 130 of about 80,898 (289)
A Flexible Path for Human and Robotic Space Exploration [PDF]
, 2010 During the summer of 2009, a flexible path scenario for human and robotic space exploration was developed that enables frequent, measured, and publicly notable human exploration of space beyond low-Earth orbit (LEO).
Adams, Robert B. +5 more
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Mars sample return: Site selection and sample acquisition study [PDF]
Various vehicle and mission options were investigated for the continued exploration of Mars; the cost of a minimum sample return mission was estimated; options and concepts were synthesized into program possibilities; and recommendations for the next ...
Nickle, N.
core +1 more source
Extension of Martian orbits using continuous low-thrust propulsion [PDF]
, 2012 There has recently been significant interest in exploration of the Martian surface and atmosphere with a view to future human exploration. Thus missions must be developed which are responsive to these scientific goals.
Anderson, Pamela +2 more
core
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Booster Obsolescence and Life Extension (BOLE) for Space Launch System (SLS) [PDF]
A human mission to the moon and Mars is the stated space exploration goal of the United States and the international community. To achieve these goals, NASA is developing the Space Launch System (SLS) and the Orion crew capsule as key elements in the ...
Fuller, Michael E. +4 more
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Participatory Technology Assessment for Mars Mission Planning: Public Values and Rationales [PDF]
Public support and interest are needed to design an ambitious human spaceflight program. However, it is difficult to understand what the public values and would support.
Bertrand, Pierre +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Space resources. Volume 4: Social concerns [PDF]
Space resources must be used to support life on the Moon and exploration of Mars. This volume, Social Concerns, covers some of the most important issues which must be addressed in any major program for the human exploration of space.
Duke, Michael B. +2 more
core +1 more source