Results 91 to 100 of about 1,106,622 (296)

MARS EXPRESS: Mission Status, Recent Findings and future Plans [PDF]

, 2017
International audienceMars Express has entered its second decade in orbit in excellent health. Characterization of geological processes and landforms on Mars on a local-to- regional scale by HRSC camera constrained the mar- tian geological activity in ...
Giuranna, Marco, Martin, P., Plaut, J., Cardesin-Moinelo, A., Martin, Patrick, Jaumann, R., Holmström, Mats, Plaut, Jeffrey J., Titov, Dmitrij V., Määttänen, A., Forget, F., Forget, François, MEX SGS Team, Määttänen, Anni, Jaumann, Ralf, Duxbury, T., Titov, D., Bibring, Jean-Pierre, Montmessin, F., Pätzold, M., Duxbury, Tom, Gonzalez-Galindo, Francisco, Cardesin, A., Montmessin, Franck, Pätzold, Martin, González-Galindo, F., Orosei, Roberto, Holmström, M.   +27 more
core  

Rootless cones on Mars indicating the presence of shallow equatorial ground ice in recent times [PDF]

, 2001
High resolution Mars Orbiter Camera (MOC) images have revealed the existence of clusters of small cones in the Cerberus plains, Marte Valles, and Amazonis Planitia, Mars.
McEwen, A. S., Lanagan, P. D., Keszthelyi, L. P., Thordarson, T.   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Erosion rate and previous extent of interior layered deposits on Mars revealed by obstructed landslides [PDF]

, 2014
We describe interior layered deposits on Mars that have obstructed landslides before undergoing retreat by as much as 2 km. These landslides differ from typical Martian examples in that their toe height increases by as much as 500 m in a distinctive ...
Warner, N.H., Grindrod, Peter M.
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Influence of mineralogy on the preservation of amino acids under simulated Mars conditions [PDF]

, 2016
publisher: Elsevier articletitle: Influence of mineralogy on the preservation of amino acids under simulated Mars conditions journaltitle: Icarus articlelink: http://dx.doi.org/10.1016/j.icarus.2016.05.029 content_type: article copyright: © 2016 The ...
dos Santos R, Martins, Zita, Patel, M, Martins, Z, Cuadros J, Patel, Manish, Martins Z, dos Santos, Renato, dos Santos, R, Patel M, Cuadros, Javier, Cuadros, J   +11 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Numerical integration and analysis of mars orbital dynamics

Frontiers in Astronomy and Space Sciences
IntroductionThe high-precision numerical ephemeris of Mars is important for its mission planning, spacecraft navigation, and solar system dynamics studies.MethodsThis study systematically compares the dynamical models employed in the DE441, EPM2021 ...
Shuhao Feng, Yilong Han, Shanhong Liu, Shanhong Liu, Kai Tang, Jianguo Yan   +5 more
doaj   +1 more source