Results 101 to 110 of about 1,106,622 (296)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Mars Express tracking and orbit determination trials with Chinese VLBI network

, 2010
With strong support from European Space Agency (ESA), Shanghai Astronomical Observatory (SHAO) organized a tracking and orbit determination trails using Chinese VLBI Network (CVN) to track Mars Express, the first Mars probe launched by ESA.
Ma MaoLi, Zheng WeiMin, Cao JianFeng, Hu XiaoGong, Huang Yong   +4 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Enhanced Oxygen Ion Outflow at Earth and Mars due to the Concurrent Impact of a Stream Interaction Region

The Astrophysical Journal
One of the major processes that solar wind drives is the outflow and escape of ions from the planetary atmospheres. The major ion species in the upper ionospheres of both Earth and Mars is O ^+ , and hence it is more likely to dominate the escape process.
Indu Venugopal, Smitha V. Thampi, Ankush Bhaskar, V. Venkataraman   +3 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The MEDUSA and MicroMED Experiments for the ExoMars Space Programme to Perform In Situ Analysis of Martian Dust [PDF]

, 2011
This thesis describes the work for the PhD in Aerospace, Naval and Total Quality Management of the University of Naples “Federico II” from 2008 to 2011. The work was mostly performed at National Institute of Astrophysics (INAF) - Astronomical Observatory
Ventura, Sergio
core   +1 more source

Automated Shape-model-based Astrometry of Phobos from Mars Express Super Resolution Channel Images

The Astronomical Journal
High-resolution spacecraft images provide important astrometric constraints for orbit refinement, but measurements of resolved bodies are often limited by labor-intensive control-point selection and the difficulty of achieving consistent reductions over ...
Wangxin Lai, Qingfeng Zhang, Rui Zhang, Kai Tang, Chunyu Ding, Zhan Li, Haipeng Wang   +6 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Mars Express: Genesis and Infancy

Space Science Reviews
Abstract This paper describes the flow of events which led ESA to select this Mars Express mission for a launch in 2003, following the failure of the Russian Mars 96 in 1996. The unique genesis of Mars Express is reflected in its system design, the payload selected, and the operation strategy.
Bibring, Jean-Pierre, Bertaux, Jean-Loup, Bonnet, Roger, Bonneville, Richard, Korablev, Oleg, Langevin, Yves, Frécon, Luc, Poinsignon, Vincent, Schmidt, Rudy   +8 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source