Presence of CRISPR CAS-Like Sequences as a Proposed Mechanism for Horizontal Genetic Exchanges between Trichomonas vaginalis and Its Associated Virus: A Comparative Genomic Analysis with the First Report of a Putative CRISPR CAS Structures in Eukaryotic Cells. [PDF]
Biomed Res Int, 2023 Introduction. Trichomonas vaginalis genome is among the largest genome size and coding capacities. Combinations of gene duplications, transposon, repeated sequences, and lateral gene transfers (LGTs) have contributed to the unexpected large genomic size and diversity. This study is aimed at investigating genomic exchange and seeking for presence of the
Kenarkoohi A +11 more
europepmc +2 more sources
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2018 E. Koonin
semanticscholar +3 more sources
Megaviruses contain various genes encoding for eukaryotic vesicle trafficking factors
Traffic, Volume 23, Issue 8, Page 414-425, August 2022., 2022 Giant viruses enter their eukaryotic host cells by phagocytosis. For reproduction, they hijack the host cell's membranes by an unknown mechanism. Here, we found that giant viruses express several core factors of the eukaryotic vesicle fusion machinery, including SNARE, Rab, SM proteins, and the disassembly protein NSF.
Dany Khalifeh +2 more
wiley +1 more source
Diversity of Amoeba-Associated Giant Viruses Isolated in Algeria
Diversity, 2020 The discovery of several giant amoeba viruses has opened up a novel area in the field of virology. Despite this, knowledge about ecology of these viruses remains patchy. In this study, we aimed to characterize the diversity of giant viruses in Algeria by
Hadjer Boudjemaa +3 more
doaj +1 more source
Extension of the viral ecology in humans using viral profile hidden Markov models. [PDF]
PLoS ONE, 2018 When human samples are sequenced, many assembled contigs are "unknown", as conventional alignments find no similarity to known sequences. Hidden Markov models (HMM) exploit the positions of specific nucleotides in protein-encoding codons in various ...
Zurab Bzhalava +2 more
doaj +1 more source
The structure of a virus-encoded nucleosome. [PDF]
Nat Struct Mol Biol, 2021 Valencia-Sánchez MI +12 more
europepmc +2 more sources
Exposure to Mimivirus collagen promotes arthritis [PDF]
, 2014 Collagens, the most abundant proteins in animals, also occur in some recently described nucleocytoplasmic large DNA viruses such as Mimiviridae, which replicate in amoebae.
Gay, Steffen +5 more
core +1 more source
Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms. [PDF]
, 2012 Based on Darwin's concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions, and duplication were streaming the genomes of living organisms.
Bertelli, C., Greub, G.
core +2 more sources
Lausannevirus Encodes a Functional Dihydrofolate Reductase Susceptible to Proguanil. [PDF]
, 2017 Lausannevirus belongs to the family Marseilleviridae within the group of nucleocytoplasmic large DNA viruses (NCLDVs). These giant viruses exhibit unique features, including a large genome, ranging from 100 kb to 2.5 Mb and including from 150 to more ...
Gauye, F. +3 more
core +1 more source