Results 11 to 20 of about 4,835,904 (211)

GPCR dimerization: Drug discovery aspects and targets in renin‐angiotensin systems

open access: yesFASEB BioAdvances
G protein‐coupled receptors (GPCRs), which play crucial roles in various physiological functions, often assembled into dimers and higher‐order oligomers. This oligomerization phenomenon has been observed in diverse physiological and pathological contexts,
Tahmid Faisal, Tahir Hussain
doaj   +2 more sources

Machine learning for optimizing mAs in KUB radiography with metal implants. [PDF]

open access: yesJ Appl Clin Med Phys
Abstract Background and purpose Kidney–ureter–bladder (KUB) radiography is a common examination that exposes patients to a higher radiation dose and increased cancer risk; therefore, it is important to estimate suitable exposure factors for each patient prior to radiography.
Chen WX   +4 more
europepmc   +2 more sources

Chronic alcohol intake regulates expression of SARS‐CoV2 infection‐relevant genes in an organ‐specific manner

open access: yesAlcohol, Clinical and Experimental Research, Volume 47, Issue 1, Page 76-86, January 2023., 2023
Our study focusses on the expression of SARS‐CoV2 infection relevant genes in different organs in three rat models of ethanol intake. We found a consistent upregulation of Ace2 gene expression in the lung, whereas other organs showed also up‐regulation of Ace2 and Mas but in a less consistent manner across the animal models.
Marion M. Friske   +5 more
wiley   +1 more source

In situ 13C solid‐state polarization transfer NMR to follow starch transformations in food

open access: yesMagnetic Resonance in Chemistry, Volume 60, Issue 7, Page 671-677, July 2022., 2022
The comparison of 13C solid‐state magic angle spinning (MAS) NMR experiments based on two different polarization transfers—CP and INEPT—can be used to investigate the state of starch and other molecules in starch‐based food products. Line shapes and peak positions, as well as the interplay between the CP and INEPT intensities, provide information ...
Agnieszka Nowacka‐Perrin   +3 more
wiley   +1 more source

You cannot fight the pressure: Structural rearrangements of active pharmaceutical ingredients under magic angle spinning

open access: yesMagnetic Resonance in Chemistry, Volume 60, Issue 6, Page 572-582, June 2022., 2022
Structural changes of different amorphous and crystalline active pharmaceutical ingredients under magic angle spinning (MAS) conditions due to the increased pressure are shown. The possibility of detecting such changes by X‐ray powder diffraction, 19F MAS NMR, and 1H‑13C FSLG HETCOR/MAS NMR spectra is discussed with the latter being able to detect even
Sebastian Scheidel   +3 more
wiley   +1 more source

Transadapting fable into a parable for Indonesian Muslim children: Strategies and impacts

open access: yesIndonesian Journal of Applied Linguistics, 2022
The demand for domestication and localization of children’s literature compels translators to not only translate the texts but also transadapt them. Significant problems arise when the texts have to fit the cultures and religions of the target users ...
SF. Luthfie Arguby Purnomo   +7 more
doaj   +1 more source

Power and limitations of electrophoretic separations in proteomics strategies [PDF]

open access: yes, 2009
Proteomics can be defined as the large-scale analysis of proteins. Due to the complexity of biological systems, it is required to concatenate various separation techniques prior to mass spectrometry.
Aebersold   +225 more
core   +4 more sources

Molecular characterization of rice (Oryza sativa L.) genotypes for drought tolerance using two SSR markers

open access: yesElectronic Journal of Plant Breeding, 2017
Plant growth as well as productivity of rice (Oryza sativa L.), the major cereal and staple food of millions, is significantly affected by numerous biotic and abiotic stresses.
Shaheen A. Salam   +3 more
doaj   +1 more source

An Embedded Platform for Testbed Implementation of Multi-Agent System in Building Energy Management System

open access: yesEnergies, 2019
This paper presents a hardware testbed for testing the building energy management system (BEMS) based-on the multi agent system (MAS). The objective of BEMS is to maximize user comfort while minimizing the energy extracted from the grid.
Aryuanto Soetedjo   +2 more
doaj   +1 more source

The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway

open access: yesIUBMB Life, Volume 72, Issue 11, Page 2241-2259, November 2020., 2020
Abstract This article presents a personal and critical review of the history of the malate–aspartate shuttle (MAS), starting in 1962 and ending in 2020. The MAS was initially proposed as a route for the oxidation of cytosolic NADH by the mitochondria in Ehrlich ascites cell tumor lacking other routes, and to explain the need for a mitochondrial ...
Piet Borst
wiley   +1 more source

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