Results 121 to 130 of about 103,725 (252)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Masculinity and the Bible Survey, Models, and Perspectives

open access: yes
Intro -- Contents -- Masculinity and the Bible: Survey, Models, and Perspectives -- Abstract -- Keywords -- Introduction -- Part 1. Masculinity Studies: Development and Trends -- Introduction -- Origins of Masculinity Studies -- Masculinity and (Global ...
Smit, Peter-Ben.
core  

“Note on sex for the aged widower”: On André Brink’s The Rights of Desire

open access: yesTydskrif vir Letterkunde, 2018
This article examines the representation of masculinity in André Brink’s novel, The Rights of Desire. Following a remark in Roger Boylan’s review of the novel in the Boston Review; this analysis concentrates on Brink’s depiction of Afrikaner masculinity ...
Marius Crous
doaj  

The Image of Incriminated Masculinity in Crime Narratives - A Hegemonic Approach

open access: yesHoryzonty Wychowania
RESEARCH OBJECTIVE: The aim of this article is to characterize the portrayal of incriminated masculinity in crime narratives. THE RESEARCH PROBLEM AND METHODS: Three narrative tendencies creating the image of masculinity were identified through a ...
Olga Pankalla
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Foucault’s men, or what have masturbating boys and ancient men to do with masculinity?

open access: yes, 2020
This chapter provides an overview of how the work of Michel Foucault has been discussed within masculinity studies and feminist theory, and re-reads Focuault’s work as theories about men and masculinity.
Gottzén, Lucas,
core  

Social Games and the Shaping of Troubadour Masculinity: Notes on Some Cases from 12th and 13th Centuries

open access: yesTerminus
The aim of this article is to outline the characteristics of the troubadouresque model of masculinity based on cases from 12th- and 13th-century poetry.The troubadouresque model of masculinity was ...
Michał Sawczuk
doaj   +1 more source

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