Results 61 to 70 of about 2,431,612 (292)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

In vivo production of entomopathogenic nematodes using Galleria mellonella: costs and effect of diets on nematode pathogenicity

open access: yesJournal of Nematology, 2019
Five separate diets – beeswax (BW), glycerol (Gly), and three types of dog croquettes (DC1, DC2, and DC3) – were used to rear larvae of the greater wax moth, Galleria mellonella.
Kotchofa Régina, Baimey Hugues
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Mass Rearing of a Mirid Predator

open access: yes, 1990
This article 'Mass Rearing of a Mirid Predator' appeared in the International Rice Research Newsletter series, created by the International Rice Research Institute (IRRI). The primary objective of this publication was to expedite communication among scientists concerned with the development of improved technology for rice and for rice based cropping ...
openaire   +2 more sources

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Spine morphology of neurons in the Avian forebrain is affected by rearing conditions

open access: yes, 1994
Rollenhagen A, Bischof H-J. Spine morphology of neurons in the Avian forebrain is affected by rearing conditions. Behavioral and Neural Biology. 1994;62(2):83-89.An area of the caudal forebrain of male zebra finches, the Archi-Neostriatum caudale (ANC ...
Rollenhagen, Astrid   +1 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Exploitation of the Medfly Gut Microbiota for the Enhancement of Sterile Insect Technique: Use of Enterobacter sp. in Larval Diet-Based Probiotic Applications. [PDF]

open access: yesPLoS ONE, 2015
The Mediterranean fruit fly (medfly), Ceratitis capitata, is a pest of worldwide substantial economic importance, as well as a Tephritidae model for sterile insect technique (SIT) applications.
Antonios A Augustinos   +5 more
doaj   +1 more source

Appendix C. Sample sizes of adult females used to estimate brood-rearing-specific estimates of annual survival.

open access: yes, 2016
Sample sizes of adult females used to estimate brood-rearing-specific estimates of annual ...
James S. Sedinger (384877)   +3 more
core   +1 more source

Mass rearing of Anopheles albimanus.

open access: yes, 1980
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +1 more source

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