The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Mass appraisal: modelli sperimentali per il mercato immobiliare di Roma
Saverio Miccoli
doaj +1 more source
Diabetic Eye Screening Attendance Among Minority Ethnic and Other Inequality-Affected Populations in the United Kingdom: A Systematic Review of Associated Factors, Barriers, Facilitators and Interventions. [PDF]
Khalid H, Andaleeb F.
europepmc +1 more source
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley +1 more source
Quality of osteoporosis management guidelines produced in China: a systematic review. [PDF]
Liu X +5 more
europepmc +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Post-Traumatic Growth in Esophageal Cancer Patients: A Latent Profile Analysis for Targeted Psychosocial Care. [PDF]
Cao Z, Jia P, Zhang A.
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Beyond BMI: The Role of Visceral Adipose Tissue in Cardiometabolic Risk Stratification Among Children and Adolescents with Obesity-A Systematic Review. [PDF]
Zahorowska A +8 more
europepmc +1 more source

