Epitope of antiphospholipid antibodies retrieved from peptide microarray based on R39‐R43 of β2‐glycoprotein I [PDF]
Research and Practice in Thrombosis and Haemostasis, 2022 Background Antiphospholipid antibody (aPL) syndrome (APS) is an autoimmune disease characterized by the presence of antiphospholipid antibodies and thromboembolic or pregnancy complications.
Marc Moghbel +8 more
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Penicillin-sensitive DD-carboxypeptidases from Streptomyces strains R39 and K11 [PDF]
Biochemistry, 1972 The two penicillin-sensitive DD-carboxypeptidases from Streptomyces R39 and K11 are anionic at pH 8. They specifically recognize a C-terminal L-R3-D-alanyl-D sequence with a long side chain at the R3 position. The two enzymes differ from each other with respect to: (1) the effects of ionic strength on activity, (2) the influence exerted on activity by ...
M Nieto, Manuel Nieto, M Leyh-Bouille
exaly +5 more sources
Purification and properties of the exocellular β-lactamase of a Actinomadura strain R39 [PDF]
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982 The exocellular beta-lactamase (penicillin amido-beta-lactamhydrolase, EC 3.5.2.6) of Actinomadura R39 consists of one single polypeptide chain of molecular weight about 15 200. It exhibits a highly asymmetrical shape, has a low isoelectric point (at pH 5.0) and contains about 9.3% (w/w) of a polydeoxyribonucleotide with which it forms a rather stable ...
Duez, Colette +5 more
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Site-directed mutagenesis of the Actinomadura R39 DD-peptidase [PDF]
Biochemical Journal, 1997 The role of various residues in the conserved structural elements of the Actinomadura R39 penicillin-sensitive DD-peptidase has been studied by site-directed mutagenesis. Replacement of Ser-298 of the ‘SDN loop’ by Ala or Gly significantly decreased the kcat/Km value for the peptide substrate, but only by a factor of 15 and had little effect on the ...
G H, Zhao +7 more
openaire +4 more sources
The J-shape of β2GPI reveals a cryptic discontinuous epitope across domains I and II [PDF]
Journal of Structural Biology: XBeta-2-Glycoprotein I is the main target for pathogenic antiphospholipid syndrome autoantibodies. It can adopt several conformations, including an O-shape and two more linear J- and S-shapes.
C.J. Lalaurie +5 more
doaj +2 more sources
R39. Ps. Arnaldus de Vilanova [PDF]
, 2007 This chapter presents a detailed repertory which gives incipit and explicit as well as information on author, date, editions and a summary of the contents of the dialogues on Philosopher's stone, Natural treasure, Secret operations, Secrets of matter and Instructed stone written by Arnaldus De Villanova in the Middle Ages.
exaly +5 more sources
The effect of induced molting on the testicular physiological remodeling in no-semen roosters [PDF]
BMC GenomicsBackground The fertility of roosters significantly impacts the economic outcome of the poultry industry. However, it is common for some roosters to fail to produce semen during production, and the underlying reasons remain largely unclear.
Wanying Xie +8 more
doaj +2 more sources
Crystal Structure of the Actinomadura R39 DD-peptidase Reveals New Domains in Penicillin-binding Proteins* [PDF]
Journal of Biological Chemistry, 2005 Actinomadura sp. R39 produces an exocellular DD-peptidase/penicillin-binding protein (PBP) whose primary structure is similar to that of Escherichia coli PBP4. It is characterized by a high beta-lactam-binding activity (second order rate constant for the acylation of the active site serine by benzylpenicillin: k2/K = 300 mm(-1) s(-1)).
Stéphanie Petrella +2 more
exaly +4 more sources
Numerical Study on Chemical Kinetic Characteristics of Counterflow Diffusion Flame Extinction of Methane/Ammonia/Air Flame under High Pressure or Air Preheating Temperature [PDF]
MoleculesGreen ammonia has become an increasingly popular fuel in recent years because of its combustion process without carbon oxide release. Adding ammonia to methane fuel for co-combustion has become one of the important research topics in the current ...
Ying Chen +3 more
doaj +2 more sources
ESTIMATION OF COMBINING ABILITY AND HETEROSIS FOR SOME MAIZE INBRED LINES AND ITS SINGLE CROSSES [PDF]
Journal of Plant Production, 2015 Two field experiments were conducted out during 2012 and 2013 seasons to estimate combining ability, heterosis for six inbred lines (Three American inbreds: P97, B73and Oh.43 and three Egyptian inbred lines: R39, Inb.1021 and Inb.1004) and its F1 crosses.
A. Attia +4 more
doaj +1 more source