Results 81 to 90 of about 23,081,151 (331)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

High precise dating on the variation of the Asian summer monsoon since 37 ka BP

open access: yesScientific Reports, 2021
Comprehensive comparison of paleoclimate change based on records constrained by precise chronology and high-resolution is essential to explore the correlation and interaction within earth climate systems.
Ting-Yong Li   +9 more
doaj   +1 more source

Using satellite laser ranging to measure ice mass change in Greenland and Antarctica

open access: yes, 2017
. A least squares inversion of satellite laser ranging (SLR) data over Greenland and Antarctica could extend gravimetry-based estimates of mass loss back to the early 1990s and fill any future gap between the current Gravity Recovery and Climate ...
J. Bonin, D. Chambers, M. Cheng
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Stalagmite-inferred variability of the Asian summer monsoon during the penultimate glacial–interglacial period [PDF]

open access: yesClimate of the Past, 2014
The orbital-timescale dynamics of the Quaternary Asian summer monsoons (ASM) are frequently attributed to precession-dominated northern hemispheric summer insolation.
T.-Y. Li   +7 more
doaj   +1 more source

Sympathy for the devil: captive-management style did not influence survival, body-mass change or diet of Tasmanian devils 1 year after wild release

open access: yesWildlife research (East Melbourne), 2016
Context. The value of captive breeding for recovery programs of endangered carnivorous mammals is often questioned because of low post-release survival reported for founder animals following translocation. Aims.
T. Rogers, S. Fox, D. Pemberton, P. Wise
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Device for monitoring a change in mass in varying gravimetric environments [PDF]

open access: yes, 1974
A remotely operable device for detecting changes as they occur in the mass of a selected specimen is described. The device is characterized by a balance beam including at one end a support for receiving a specimen having a changing mass and suspension ...
Valinsky, J. P.
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

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