Results 51 to 60 of about 2,288,602 (308)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Perception of Social and Behaviour Change Communication Media in Cross River State, Nigeria [PDF]

open access: yes, 2016
In the wake of increased interventions into health and social problems arising from various behaviours in Cross River State, this paper is set to ascertain the most effective media that can be utilized for effective communication.
Iyorza, Stanislaus
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Re-Viewing the Mass Communication Education Curriculum. Case for Language/Linguistics, Communication Synergy. [PDF]

open access: yes, 2018
Curriculum review of any academic curriculum is one way of demonstrating the dynamism of such discipline. Mass Communication as a dynamic discipline is one such beneficiary of curriculum review.
Iwuchukwu, Godwin C. S.   +1 more
core  

Position-dependent mass models and their nonlinear characterization

open access: yes, 2007
We consider the specific models of Zhu-Kroemer and BenDaniel-Duke in a sech$^{2}$-mass background and point out interesting correspondences with the stationary 1-soliton and 2-soliton solutions of the KdV equation in a supersymmetric framework.Comment: 8
B Bagchi   +10 more
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

數位時代下媒體素養教育政策再思考 Rethinking Media Literacy Policy in the Digital Internet Era

open access: yesJournal of Research in Education Sciences, 2020
教育部自2002年公布《媒體素養教育政策白皮書》以來,至今未再提出修正或新版的全國性媒體素養教育政策。然而,現今媒體環境已有相當大的改變,例如從社群媒體到自媒體,乃至新興的人工智慧科技,這些新科技的出現,意味著我們很難再用原有的框架去思考現今的媒體素養教育政策。因此,《媒體素養教育政策白皮書》實有必要修正及更新。本研究透過檢視媒體素養政策文獻和臺灣媒體素養政策回顧,對數位網路時代的媒體素養教育政策提出五個建議方向:一、重新思考「媒體素養」概念,解析新媒體環境生態;二、建立以「創用者」(prosumer ...
林玉鵬 Yu-Peng Lin   +2 more
doaj   +1 more source

A Web Interface for Analyzing Hate Speech

open access: yesFuture Internet, 2021
Social media services make it possible for an increasing number of people to express their opinion publicly. In this context, large amounts of hateful comments are published daily.
Lazaros Vrysis   +7 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

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