Results 91 to 100 of about 981,872 (286)

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Experience American science of communication for Ukraine in the field of information democracy

Американська історія і політика, 2016
In the article the scientific exploration of American experts communication. Determined that communication integrates research and development experts in sociology, political science, art, ethnology, journalism, law, philosophy, psychology and others ...
Mytko Antonina
doaj   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Newsmaking Criminology in the 21st Century: Forming the Public Opinion under the New Reality

Journal of Digital Technologies and Law
Objective: to study the concept of newsmaking criminology and its relevance in the current conditions of mass media development.Methods: the methodological basis of the work consists of general scientific, social, and special-legal methods of cognition ...
V. A. Babaeva
doaj   +1 more source

Neural Network‐Based Permittivity Engineering of Magnetic Absorbers for Customizable Microwave Absorption

Advanced Science, EarlyView.
A neural network‐enabled permittivity engineering paradigm is introduced, transcending traditional trial‐and‐error design. By decoupling electromagnetic parameters and screening a high‐throughput feature space, an ultrathin (1.0 mm) magnetic absorber is inversely designed, experimentally achieving a superior and customizable 5.1 GHz bandwidth and ...
Chenxi Liu, Jinzhe Li, Sen Li, Zhongqiu Guo, Yao Chen, Tian Li, Renchi Qin, Jiaxu Sun, Yongxi Lu, Fanbin Meng   +9 more
wiley   +1 more source

Dirac Surface‐State Driven Broad Spectral Band Low Quantum Energy Photoresponse in Quaternary Topological BiSbSe2Te

Advanced Science, EarlyView.
Quaternary topological BiSbSe2Te are synthesized and demonstrates a broad spectral band photoresponse, ranging from infrared to terahertz and to millimeter waves, with a particular excellence on detection of low quantum energy terahertz photons. The observed photoresponse is attributed to the excitation of plasmonic nonequilibrium electrons originating
Tianning Zhang, Jinchao Tong, Jiantian Zhang, Peng Yu, Heng Luo, Luo Yan, Boyu Yang, Tiantian Huang, Junhui Ran, Yan Chen, Liujiang Zhou, Xin Chen, Ning Dai, Jianlu Wang, Junhao Chu   +14 more
wiley   +1 more source

A one-dimensional axisymmetric model for time-varying electromagnetic mitigation of plasma for alleviation of radio communication blackout

AIP Advances, 2018
A high speed vehicle passing through the atmosphere may encounter radio communication blackout, a phenomenon which is caused by the high plasma density in the plasma layer surrounding the vehicle.
Donglin Liu, Xiaoping Li, Yanming Liu, Jiahao Xu, Fan Lei, Xi Chen   +5 more
doaj   +1 more source

Proxy of democracy? : metaphors of connection as arguments against representation [PDF]

, 2012
This paper aims to assess the arguments that claim representative democracy may be enhanced or replaced by an updated electronic version. Focusing on the dimension of elections and electioneering as the core mechanism of representative democracy I will ...
Cuono, Massimo
core  

Magneto‐X Effects in Magnetic Soft Materials and Their Applications

Advanced Science, EarlyView.
This review systematically explores magnetic soft materials (MSMs), a novel class of composites that transform under magnetic fields. It catalogs fundamental “Magneto‐X” effects, classifies materials by their matrix and magnetic fillers, and highlights transformative applications in soft robotics, biomedical devices, flexible electronics, etc. Finally,
Ziyin Xiang, Xiangling Xia, Benjamin Ducharne, Yujie Ye, Jie Shang, Run‐Wei Li   +5 more
wiley   +1 more source

De lege ferenda for improvement of the Korean legal system for maritime autonomous surface ships (MASS)

Journal of International Maritime Safety, Environmental Affairs, and Shipping
With the advent of the Fourth Industrial Revolution, technologies based on Information and Communication Technology, the Internet of Things, and Artificial Intelligence are rapidly advancing.
Jiyeon Shin, Haedong Jeon
doaj   +1 more source