Results 51 to 60 of about 4,825,318 (291)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Quantitative estimate of the contribution of the surface diffusion process to mass transfer during electrochemical deposition of metals

Фізика і хімія твердого тіла, 2022
In this study, an attempt was made to quantify the contribution of the surface diffusion process to mass transfer during electrochemical deposition of metals.
A.I. Nesterenko, N.G. Nesterenko, V.N. Sakhno   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

MASS TRANSFER EFFECTS ON ACCELERATED VERTICAL PLATE IN A ROTATING FLUID WITH FIRST ORDER CHEMICAL REACTION [PDF]

Journal of Mechanical Engineering and Sciences, 2012
The precise analysis of the rotation effects on the unsteady flow of an incompressible fluid past a uniformly accelerated infinite vertical plate with variable temperature and mass diffusion has been undertaken, in the presence of a homogeneous first ...
R. Muthucumaraswamy, N. Dhanasekar, G. Easwara Prasad   +2 more
doaj  

Differentiation of placenta percreta through MRI features and diffusion-weighted magnetic resonance imaging

Insights into Imaging, 2023
Objectives To identify whether parameters measured from diffusion kurtosis and intravoxel incoherent motion help diagnose placenta percreta. Methods We retrospectively enrolled 75 patients with PAS disorders including 13 patients with placenta percreta ...
Hang Li, Tao Lu, Mou Li, Yishuang Wang, Feng Zhang, Yi Yuan, Meilin Zhu, Xinyi Zhao   +7 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Effects of a magnetic field on circulation in an advanced inclined isothermal sectional surface with mass and heat transfer

International Journal of Applied Mechanics and Engineering
The purpose of this study is to investigate the influence of an external magnetic field on heat and mass distribution across a moving isothermal sectional surface. The temperature is elevated to ( ) of the plate.
SUNDAR RAJ MARIADOSS, NAGARAJAN GNANAVEL, RAJARAMAN R, SARAVANAN B, Muthucumaraswamy R   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source