Results 61 to 70 of about 386,001 (265)
Diffusion subject to the specification of mass
The paper demonstrates that the problem \[ u_ t=u_{xx}+s(x,t),\quad ...
Cannon, John R., van der Hoek, John
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Modeling amperometric biosensors based on allosteric enzymes
Computational modeling of a biosensor with allosteric enzyme layer was investigated in this study. The operation of the biosensor is modeled using non-stationary reaction-diffusion equations.
Liutauras Ričkus
doaj +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
ObjectiveInvestigating grout diffusion patterns and predicting the grouting range hold great significance for coal gangue grouting and filling engineering in goaves.
Yifan ZENG +13 more
doaj +1 more source
A Novel Intelligent Recommendation Algorithm Based on Mass Diffusion
Social recommendation algorithm is a common tool for recommending interesting or potentially useful items to users amidst the sea of online information.
Guanglai Tian +3 more
doaj +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Mass-dependence of self-diffusion coefficients in disparate-mass binary fluid mixtures
Self-diffusion coefficients of a binary fluid mixture with components differing only in their particle masses are studied, in particular the case when mass ratio μ of light and heavy particles tends to zero.
I. Binas, I. Mryglod
doaj +1 more source

