Results 71 to 80 of about 26,344 (283)

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Healthcare demand in response to rabies elimination campaigns in Latin America.

PLoS Neglected Tropical Diseases, 2019
The World Health Organization, the World Organization for Animal Health, and the Food and Agriculture Organization have resolved to eliminate human rabies deaths due to dog bites by 2030, and the Vaccine Alliance (Gavi) has added human rabies vaccines to
Jonathan Yoder, Elisabeth Younce, Felix Lankester, Guy H Palmer   +3 more
doaj   +1 more source

Recombinant expression systems: the obstacle to helminth vaccines? [PDF]

, 2007
A
Claerebout, Edwin, De Maere, Veerle, Geldhof, Peter, Vercruysse, Jozef   +3 more
core   +2 more sources

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

One million dog vaccinations recorded on mHealth innovation used to direct teams in numerous rabies control campaigns [PDF]

, 2018
BackgroundCanine transmitted rabies kills an estimated 59,000 people annually, despite proven methods for elimination through mass dog vaccination. Challenges in directing and monitoring numerous remote vaccination teams across large geographic areas ...
A Belotto, A Bernabe-Ortiz, AD Gibson, AD Gibson, Andrew D. Gibson, Barend M.deC. Bronsvoort, Charles E Rupprecht, Dagmar Mayer, DF Malanga, DM Aanensen, EA Ferguson, Frederic Lohr, H Bourhy, Ian G. Handel, JE Teng, JL Burdon Bailey, Jordana L. Burdon Bailey, K Hampson, K Hampson, K Thriemer, K Tohma, Kate Shervell, Luke Gamble, M Ali, M Kaare, M Mwabukusi, M Stanton, MC Schneider, MDW Widyastuti, MF De Carvalho, Richard J. Mellanby, RM Wallace, Ryan M. Wallace, S Cleaveland, S Cleaveland, S Cleaveland, S Mazeri, S Sherin, S Welburn, SC Welburn, SS Kim, Stella Mazeri, T Jibat, T Lembo, W Avilés, Z Mtema   +45 more
core   +2 more sources

Microwave‐Assisted Aqueous Synthesis of Gelatin‐Norbornene for Hydrogel Crosslinking and Bioprinting

Advanced Materials Technologies, EarlyView.
A microwave‐assisted reaction is utilized to synthesize gelatin‐norbornene (GelNB), achieving a high degree of norbornene functionalization while reducing the macromer's upper critical solution temperature. The resulting GelNB macromer has high solubility at room temperature, facilitating light‐based 3‐dimensional (3D) printing of thiol‐norbornene ...
Jonathan B. Bryan, Chien‐Chi Lin
wiley   +1 more source

Evaluating the role of surgical sterilisation in canine rabies control: A systematic review of impact and outcomes.

PLoS Neglected Tropical Diseases, 2020
Current recommendations for the elimination of canine-mediated human rabies focus on mass dog vaccination as the most feasible and cost-effective strategy.
Abi Collinson, Malcolm Bennett, Marnie L Brennan, Rachel S Dean, Jenny Stavisky   +4 more
doaj   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Factors associated with the rabies vaccination status of dogs in households in Beni City, D.R. Congo

Onderstepoort Journal of Veterinary Research
Human rabies transmitted by dogs still kills thousands of people each year worldwide. Dog bites are common in the city of Beni (Democratic Republic of Congo), which shows low rabies vaccination coverage.
Prince D. Kimpanga, Emery K. Taghembwa, Gauthier M. Mubenga, Jean-Marie T. Makwera, Norbert M. Muhongya, Odrade B. Chabikuli, Justin M. Masumu   +6 more
doaj   +1 more source