Results 51 to 60 of about 3,447,126 (242)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The influence of shift work on the psychomotor capabilities of emergency medicine residents

Journal of the American College of Emergency Physicians Open, 2021
Objective Shift work affects health status of healthcare providers and patients. We assessed the effect of shift work on psychomotor activities of emergency medicine residents of 3 university hospitals.
Mehrnoosh Aligholi Zahraie, Farshid Alaedini, Pooya Payandemehr, Soheil Saadat, Mehran Sotoodehnia, Maryam Bahreini   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Development of a mass-gathering triage tool: An Australian perspective [PDF]

, 2017
Many health service organizations deploy first responders and health care professionals to mass gatherings to assess and manage injuries and illnesses. Patient presentation rates (PPRs) to on-site health services at a mass gathering range from 0.48-170 ...
Ranse, Jamie, Julia Morphet, Rebecca Roitman, Roitman, Rebecca, Matt Cannon, Morphet, Julia, Jamie Ranse, Cannon, Matt   +7 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Environment, Human, Problems, Needs & Information! How dose arrange this puzzle? What is the information gathering (IG)? [PDF]

, 2007
The environment is a field that interaction between world elements was occurred on it. The environment produces some information, and affects other elements that exist on that field. This interaction can be defined as processes.
Farhadpoor, Mohammadreza
core   +1 more source

Enhancing Infectious Disease Preparedness in Rome: The Lazio Regional Network During the 2025 Jubilee

Tropical Medicine and Infectious Disease
In 2025, Rome hosted the Catholic Jubilee, recording over 33 million cumulative pilgrim attendances while simultaneously facing the death of Pope Francis, the election of Pope Leo XIV, and a regional West Nile Virus (WNV) outbreak.
Gaetano Maffongelli, Andrea Bongiovanni, Alessandra D’Abramo, Erica Binetti, Laura Scorzolini, Claudia Palazzolo, Gabriella De Carli, Alessandro Agresta, Francesco Vairo, Emanuele Nicastri   +9 more
doaj   +1 more source

Mass Gatherings and Respiratory Disease Outbreaks in the United States - Should We Be Worried? Results from a Systematic Literature Review and Analysis of the National Outbreak Reporting System.

PLoS ONE, 2016
BackgroundBecause mass gatherings create environments conducive for infectious disease transmission, public health officials may recommend postponing or canceling large gatherings during a moderate or severe pandemic.
Jeanette J Rainey, Tiffani Phelps, Jianrong Shi   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Mass observation / by Mass Observation.

, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core