Results 21 to 30 of about 580 (166)

Healthcare policies, precautionary measures and outcomes of mass gathering events in the era of COVID-19 pandemic: Expedited review

Journal of Infection and Public Health
With the onset of the COVID-19 pandemic in early 2020, several countries suspended or restricted mass gathering (MG) events to mitigate the risk of superspreading events.
Ahmed A. Alahmari, Anas A. Khan, Fahad A. Alamri, Yasir S. Almuzaini, Alia K. Habash, Hani Jokhdar   +5 more
doaj   +1 more source

Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus

mBio, 2014
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality.
Matthew Cotten, Simon J. Watson, Alimuddin I. Zumla, Hatem Q. Makhdoom, Anne L. Palser, Swee Hoe Ong, Abdullah A. Al Rabeeah, Rafat F. Alhakeem, Abdullah Assiri, Jaffar A. Al-Tawfiq, Ali Albarrak, Mazin Barry, Atef Shibl, Fahad A. Alrabiah, Sami Hajjar, Hanan H. Balkhy, Hesham Flemban, Andrew Rambaut, Paul Kellam, Ziad A. Memish   +19 more
doaj   +1 more source

Strengthening global health security through health early warning systems: A literature review and case study

Journal of Infection and Public Health
Disease transmission is dependent on a variety of factors, including the characteristics of an event, such as crowding and shared accommodations, the potential of participants having prolonged exposure and close contact with infectious individuals, the ...
Ahmed A. Alahmari, Yasir Almuzaini, Fahad Alamri, Reem Alenzi, Anas A. Khan   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Medical convoy: interfacility transfer of hospitalized patients during Hajj season 2019

Saudi Journal of Emergency Medicine
Background: Millions of Muslims gather annually in Makkah, Saudi Arabia, for pilgrimage (the Hajj). Some medical conditions need specialized care involving transfer outside the hospital.
Anas A. Khan, Haytham A. Sheerah, Fahad A. Alamri, Ghadah Alsaleh, Yasir Almuzaini, Ahmed A. Alahmari, Nomai N. Mukhtar, Mariyyah Alburayh, Lamis Alabdullatif, Bandar S. Almutairi, Jalal M. Alowais, Hani Johkdar   +11 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Health-related research publications on religious mass gatherings of Muslims: a bibliometric analysis (1980–2020)

Tropical Diseases, Travel Medicine and Vaccines, 2022
Objective Mass gatherings medicine is an emerging and important field at the national and international health security levels. The objective of the current study was to analyze research publications on religious mass gatherings of Muslims using ...
Waleed M. Sweileh
doaj   +1 more source