Results 131 to 140 of about 4,507,065 (293)

Mass loss from evolved stars. VI - Mass-loss mechanisms and luminosity evolution

open access: yesThe Astrophysical Journal, 1986
Molecular line data for the circumstellar envelopes of AGB red giant stars is analyzed to identify the mass-loss mechanisms and any relationships between mass loss and succeeding planetary nebulae. Mass-loss rates and outflow velocities are derived and, when compared with the stellar luminosities and optical depths of the dust envelopes, indicate that ...
openaire   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

The synergistic effects of a leaf mixture on decomposition change with a period of terrestrial exposure prior to immersion in a stream

open access: yesEcology and Evolution
The effect of mixing litter on decomposition has received considerable attention in terrestrial and aquatic (but rarely in both) ecosystems, with a striking lack of consensus in the obtained results.
Manuela Abelho, Enrique Descals
doaj   +1 more source

Orbital Migration Through Atmospheric Mass Loss

open access: yesThe Astronomical Journal
Abstract Atmospheric mass loss is thought to have strongly shaped the sample of close-in exoplanets. These atmospheres should be lost isotropically, leading to no net migration on the planetary orbit. However, strong stellar winds can funnel the escaping atmosphere into a tail trailing the planet.
Benjamin Hanf   +4 more
openaire   +3 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Assessing the natural durability of different tropical timbers in soil-bed tests

open access: yesMaderas: Ciencia y Tecnología, 2019
Ground contact speeds up timber decay because of the large number of microorganisms in soil. This study, we assessed the natural durability of seven tropical species using the European standard EN 807 (2001). We embedded samples of Dalbergia granadillo,
Serafín Colín-Urieta   +5 more
doaj  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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