Results 51 to 60 of about 1,250,119 (305)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Fire Safety Characteristics of Pine Wood Under Low Pressure and Oxygen Enrichment

Fire
Oxygen enrichment at high altitudes indoors can be effective in meeting demand. However, the high oxygen environment inevitably brings about additional fire hazards, and the specific changes are still unclear.
Sijie Ding, Xuhong Jia, Junhao Ma, Jing Tang, Wenbing Li   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The impact of mass-loss on the evolution and pre-supernova properties of red supergiants [PDF]

, 2014
The post main-sequence evolution of massive stars is very sensitive to many parameters of the stellar models. Key parameters are the mixing processes, the metallicity, the mass-loss rate and the effect of a close companion.

core  

Full-Scale Experimental Stand Development with HRR Determination from Mass Loss and CFD Model Validation

Fire
Accurate prediction of urban air quality during fire events is frequently limited by the lack of experimentally validated source terms. Current pollution dispersion models often rely on idealized input parameters that fail to capture the complex thermal ...
Mihai Dima, Iulian-Cristian Ene, Vlad Iordache, Florin Ioan Bode   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Evaluation of Loss Coefficient For Stand Alone Radiator

, 2010
In the UK, domestic heating contributes to about 40% of annual energy consumption. Effective and efficient heating systems are essential to drive the cost of heating down.
Barrans, Simon, J. Barrans, S.M. Barrans, Pillutla, G., Barrans, S. M., G. Pillutla, Mishra, R., Barrans, John, Barrans, J., Mishra, Rakesh, R. Mishra   +10 more
core   +1 more source

Mechanical Properties and Durability of Iron Tailings Concrete

Kuangchan zonghe liyong
This is an article in the field of ceramics and composites. In order to study the mechanical properties and durability of iron tailings concrete after being subjected to the dry-wet cycle of sodium sulfate solution, the compressive test, chloride ion ...
Xinya GONG, Ying LIU
doaj   +1 more source

Effect of change factors on evaporation loss based on cold end system in natural draft counter-flow wet cooling towers

Journal of Thermal Science and Technology, 2021
The water loss caused by evaporation heat dissipation is non-negligible for a natural draft counter-flow wet cooling tower (NDWCT), which is evidently influenced by many change factors.
Wei YUAN, Fengzhong SUN, Ruqing LIU, Xuehong CHEN, Ying LI   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source